SURF2 explained

surfeit 2
Hgncid:11475
Symbol:SURF2
Entrezgene:6835
Omim:185630
Refseq:NM_017503
Uniprot:Q15527
Chromosome:9
Arm:q
Band:33
Locussupplementarydata:-q34

SURF2 is a protein which in humans is encoded by the SURF2 gene.[1] SURF2 is a member of the surfeit gene family.[2] The SURF2 molecule interacts with beta-1, 4-Gal-T3, uPAR, and WDR20. As part of the surfeit gene cluster, SURF2 is one of several tightly linked genes that do not share sequence similarity. SURF2 maps to human chromosome 9q34.2 and shares a bidirectional promoter with SURF1 on the opposite strand. A bidirectional promoter activity is expected in the intergenic region between SURF1 and SURF2, as seen in mice.[3]

Notes and References

  1. Lennard A, Gaston K, Fried M . The Surf-1 and Surf-2 genes and their essential bidirectional promoter elements are conserved between mouse and human . DNA Cell Biol. . 13 . 11 . 1117–26 . November 1994 . 7702754 . 10.1089/dna.1994.13.1117.
  2. Duhig T, Ruhrberg C, Mor O, Fried M . The human Surfeit locus . Genomics . 52 . 1 . 72–8 . August 1998 . 9740673 . 10.1006/geno.1998.5372 .
  3. Web site: SURF2 Protein Human Recombinant | Surfeit 2 Antigen | ProSpec .