STX17 explained
Syntaxin 17 is a protein that in humans is encoded by the STX17 gene.[1] In horses a duplication in intron 6 causes progressive graying.[2]
See also
Further reading
- Itakura E, Kishi-Itakura C, Mizushima N . The hairpin-type tail-anchored SNARE syntaxin 17 targets to autophagosomes for fusion with endosomes/lysosomes . Cell . 151 . 6 . 1256–69 . 2012 . 23217709 . 10.1016/j.cell.2012.11.001 . free .
- Petukhova L, Duvic M, Hordinsky M, Norris D, Price V, Shimomura Y, Kim H, Singh P, Lee A, Chen WV, Meyer KC, Paus R, Jahoda CA, Amos CI, Gregersen PK, Christiano AM . Genome-wide association study in alopecia areata implicates both innate and adaptive immunity . Nature . 466 . 7302 . 113–7 . 2010 . 20596022 . 2921172 . 10.1038/nature09114 . 2010Natur.466..113P .
- Muppirala M, Gupta V, Swarup G . Syntaxin 17 cycles between the ER and ERGIC and is required to maintain the architecture of ERGIC and Golgi . Biol. Cell . 103 . 7 . 333–50 . 2011 . 21545355 . 10.1042/BC20110006 . 41507139 . free .
- Zhao ZZ, Duffy DL, Thomas SA, Martin NG, Hayward NK, Montgomery GW . Polymorphisms in the syntaxin 17 gene are not associated with human cutaneous malignant melanoma . Melanoma Res. . 19 . 2 . 80–6 . 2009 . 19209086 . 3665505 . 10.1097/CMR.0b013e328322fc45 .
- Steegmaier M, Yang B, Yoo JS, Huang B, Shen M, Yu S, Luo Y, Scheller RH . Three novel proteins of the syntaxin/SNAP-25 family . J. Biol. Chem. . 273 . 51 . 34171–9 . 1998 . 9852078 . 10.1074/jbc.273.51.34171. free .
- Hay JC, Chao DS, Kuo CS, Scheller RH . Protein interactions regulating vesicle transport between the endoplasmic reticulum and Golgi apparatus in mammalian cells . Cell . 89 . 1 . 149–58 . 1997 . 9094723 . 10.1016/s0092-8674(00)80191-9. 8682509 . free .
- Steegmaier M, Oorschot V, Klumperman J, Scheller RH . Syntaxin 17 is abundant in steroidogenic cells and implicated in smooth endoplasmic reticulum membrane dynamics . Mol. Biol. Cell . 11 . 8 . 2719–31 . 2000 . 10930465 . 14951 . 10.1091/mbc.11.8.2719.
Notes and References
- Web site: Entrez Gene: Syntaxin 17 .
- Web site: UC Davis Gray.