STRO-1 explained
STRO-1 (Stro-1 in mouse, rat, etc.) is a gene for a protein marker of mesenchymal stem cells (MSC). Molecular mass of Stro-1 is 75kD. The name STRO-1 is firstly proposed in the 1990s' as the name of an anti-CD34+-mesenchymal-stem-cell monoclonal antibody. The name "STRO-1" consists of STRO, which means mesenchyme, and "1", which means it's the first isolated monoclonal antibody to identify mesenchymal stem cells. The term "STRO-1" then was applied to the antigen for this antibody. In human body, STRO-1 exists in many organs, like lung and liver.[1] [2] [3]
See also
Notes and References
- Lin. Guiting. Liu. Gang. Banie. Lia. Wang. Guifang. Ning. Hongxiu. Lue. Tom F.. Lin. Ching-Shwun. Tissue Distribution of Mesenchymal Stem Cell Marker Stro-1. Stem Cells and Development. October 2011. 20. 10. 1747–1752. 10.1089/scd.2010.0564. 21208041. 3182037.
- Ning. H. Lin. G. Lue. TF. Lin. CS. Mesenchymal stem cell marker Stro-1 is a 75 kd endothelial antigen.. Biochemical and Biophysical Research Communications. 23 September 2011. 413. 2. 353–7. 10.1016/j.bbrc.2011.08.104. 21903091. 3183308.
- Web site: Anti-STRO1 antibody [STRO-1]]. Abcam. 2018-02-13.