STK38 explained

Serine/threonine-protein kinase 38 is an enzyme that in humans is encoded by the STK38 gene.^{[1] [2]}

Further reading

• Tripodis N . Physical map of human 6p21.2-6p21.3: region flanking the centromeric end of the major histocompatibility complex . Genome Res. . 8 . 6 . 631–43 . 1999 . 9647638 . 10.1101/gr.8.6.631. 310739 . vanc. Mason R . Humphray SJ . 3 . Davies . AF . Herberg . JA . Trowsdale . J . Nizetic . D . Senger . G . Ragoussis . J .
• Millward TA, Heizmann CW, Schäfer BW, Hemmings BA . Calcium regulation of Ndr protein kinase mediated by S100 calcium-binding proteins . EMBO J. . 17 . 20 . 5913–22 . 1998 . 9774336 . 10.1093/emboj/17.20.5913 . 1170919 .
• Strausberg RL . Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences . Proc. Natl. Acad. Sci. U.S.A. . 99 . 26 . 16899–903 . 2003 . 12477932 . 10.1073/pnas.242603899 . 139241 . vanc. Feingold EA . Grouse LH . 3 . Derge . JG . Klausner . RD . Collins . FS . Wagner . L . Shenmen . CM . Schuler . GD . 2002PNAS...9916899M . free .
• Tamaskovic R . Mechanism of Ca2+-mediated regulation of NDR protein kinase through autophosphorylation and phosphorylation by an upstream kinase . J. Biol. Chem. . 278 . 9 . 6710–8 . 2003 . 12493777 . 10.1074/jbc.M210590200 . vanc. Bichsel SJ . Rogniaux H . 3 . Stegert . MR . Hemmings . BA . free .
• Mungall AJ . The DNA sequence and analysis of human chromosome 6 . Nature . 425 . 6960 . 805–11 . 2003 . 14574404 . 10.1038/nature02055 . vanc. Palmer SA . Sims SK . 3 . Edwards . C. A. . Ashurst . J. L. . Wilming . L. . Jones . M. C. . Horton . R. . Hunt . S. E. . 2003Natur.425..805M . free .
• Bhattacharya S . Structure of the Ca2+/S100B/NDR kinase peptide complex: insights into S100 target specificity and activation of the kinase . Biochemistry . 42 . 49 . 14416–26 . 2004 . 14661952 . 10.1021/bi035089a . vanc. Large E . Heizmann CW . 3 . Hemmings . Brian A. . Chazin . Walter J. .
• Devroe E, Erdjument-Bromage H, Tempst P, Silver PA . Human Mob proteins regulate the NDR1 and NDR2 serine-threonine kinases . J. Biol. Chem. . 279 . 23 . 24444–51 . 2004 . 15067004 . 10.1074/jbc.M401999200 . free .
• Bichsel SJ, Tamaskovic R, Stegert MR, Hemmings BA . Mechanism of activation of NDR (nuclear Dbf2-related) protein kinase by the hMOB1 protein . J. Biol. Chem. . 279 . 34 . 35228–35 . 2005 . 15197186 . 10.1074/jbc.M404542200 . free .
• Jin J . Proteomic, functional, and domain-based analysis of in vivo 14-3-3 binding proteins involved in cytoskeletal regulation and cellular organization . Curr. Biol. . 14 . 16 . 1436–50 . 2004 . 15324660 . 10.1016/j.cub.2004.07.051 . vanc. Smith FD . Stark C . 3 . Wells . Clark D. . Fawcett . James P. . Kulkarni . Sarang . Metalnikov . Pavel . O'Donnell . Paul . Taylor . Paul . 2371325 . free .
• Gerhard DS . The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC) . Genome Res. . 14 . 10B . 2121–7 . 2004 . 15489334 . 10.1101/gr.2596504 . 528928 . vanc. Wagner L . Feingold EA . 3 . Shenmen . CM . Grouse . LH . Schuler . G . Klein . SL . Old . S . Rasooly . R .
• Devroe E, Silver PA, Engelman A . HIV-1 incorporates and proteolytically processes human NDR1 and NDR2 serine-threonine kinases . Virology . 331 . 1 . 181–9 . 2005 . 15582665 . 10.1016/j.virol.2004.10.023 . free .
• Amente S . Identification of proteins interacting with the RNAPII FCP1 phosphatase: FCP1 forms a complex with arginine methyltransferase PRMT5 and it is a substrate for PRMT5-mediated methylation . FEBS Lett. . 579 . 3 . 683–9 . 2005 . 15670829 . 10.1016/j.febslet.2004.12.045 . vanc. Napolitano G . Licciardo P . 3 . Monti . Maria . Pucci . Piero . Lania . Luigi . Majello . Barbara . 33475235 . free.
• Hergovich A, Bichsel SJ, Hemmings BA . Human NDR kinases are rapidly activated by MOB proteins through recruitment to the plasma membrane and phosphorylation . Mol. Cell. Biol. . 25 . 18 . 8259–72 . 2005 . 16135814 . 10.1128/MCB.25.18.8259-8272.2005 . 1234321 .
• Hergovich A, Lamla S, Nigg EA, Hemmings BA . Centrosome-associated NDR kinase regulates centrosome duplication . Mol. Cell . 25 . 4 . 625–34 . 2007 . 17317633 . 10.1016/j.molcel.2007.01.020 . free .

External links

• PDBe-KB provides an overview of all the structure information available in the PDB for Human Serine/threonine-protein kinase 38

Notes and References

1. Millward T, Cron P, Hemmings BA . Molecular cloning and characterization of a conserved nuclear serine(threonine) protein kinase . Proc Natl Acad Sci U S A . 92 . 11 . 5022–6 . Jun 1995 . 7761441 . 41840 . 10.1073/pnas.92.11.5022 . 1995PNAS...92.5022M . free .
2. Web site: Entrez Gene: STK38 serine/threonine kinase 38.