ST3GAL4 explained

is an enzyme that in humans is encoded by the ST3GAL4 gene.^{[1] [2] [3]}

Further reading

• Kalyanaraman VS, Rodriguez V, Veronese F, etal . Characterization of the secreted, native gp120 and gp160 of the human immunodeficiency virus type 1 . AIDS Res. Hum. Retroviruses . 6 . 3 . 371–80 . 1990 . 2187500 . 10.1089/aid.1990.6.371 .
• Pal R, Hoke GM, Sarngadharan MG . Role of oligosaccharides in the processing and maturation of envelope glycoproteins of human immunodeficiency virus type 1 . Proc. Natl. Acad. Sci. U.S.A. . 86 . 9 . 3384–8 . 1989 . 2541446 . 10.1073/pnas.86.9.3384 . 287137 . 1989PNAS...86.3384P . free .
• Dewar RL, Vasudevachari MB, Natarajan V, Salzman NP . Biosynthesis and processing of human immunodeficiency virus type 1 envelope glycoproteins: effects of monensin on glycosylation and transport . J. Virol. . 63 . 6 . 2452–6 . 1989 . 2542563 . 10.1128/jvi.63.6.2452-2456.1989. 250699 .
• Kozarsky K, Penman M, Basiripour L, etal . Glycosylation and processing of the human immunodeficiency virus type 1 envelope protein . J. Acquir. Immune Defic. Syndr. . 2 . 2 . 163–9 . 1989 . 2649653 .
• Robinson WE, Montefiori DC, Mitchell WM . Evidence that mannosyl residues are involved in human immunodeficiency virus type 1 (HIV-1) pathogenesis . AIDS Res. Hum. Retroviruses . 3 . 3 . 265–82 . 1988 . 2829950 . 10.1089/aid.1987.3.265 .
• Munro S . An investigation of the role of transmembrane domains in Golgi protein retention . EMBO J. . 14 . 19 . 4695–704 . 1995 . 7588599 . 10.1002/j.1460-2075.1995.tb00151.x. 394566 .
• Chang ML, Eddy RL, Shows TB, Lau JT . Three genes that encode human beta-galactoside alpha 2,3-sialyltransferases. Structural analysis and chromosomal mapping studies . Glycobiology . 5 . 3 . 319–25 . 1995 . 7655169 . 10.1093/glycob/5.3.319 .
• Sasaki K, Watanabe E, Kawashima K, etal . Expression cloning of a novel Gal beta (1-3/1-4) GlcNAc alpha 2,3-sialyltransferase using lectin resistance selection . J. Biol. Chem. . 268 . 30 . 22782–7 . 1993 . 10.1016/S0021-9258(18)41595-5 . 7901202 . free .
• Basu SS, Basu M, Li Z, Basu S . Characterization of two glycolipid: alpha 2-3sialyltransferases, SAT-3 (CMP-NeuAc:nLcOse4Cer alpha 2-3sialyltransferase) and SAT-4 (CMP-NeuAc:GgOse4Cer alpha 2-3sialyltransferase), from human colon carcinoma (Colo 205) cell line . Biochemistry . 35 . 16 . 5166–74 . 1996 . 8611500 . 10.1021/bi960239l .
• Saito S, Yamashita S, Endoh M, etal . Clinical significance of ST3Gal IV expression in human renal cell carcinoma . Oncol. Rep. . 9 . 6 . 1251–5 . 2003 . 12375029 . 10.3892/or.9.6.1251.
• Grahn A, Larson G . Identification of nine alternatively spliced alpha2,3-sialyltransferase, ST3Gal IV, transcripts and analysis of their expression by RT-PCR and laser-induced fluorescent capillary electrophoresis (LIF-CE) in twenty-one human tissues . Glycoconj. J. . 18 . 10 . 759–67 . 2003 . 12441665 . 10.1023/A:1021199300718 . 11260655 .
• Moody AM, North SJ, Reinhold B, etal . Sialic acid capping of CD8beta core 1-O-glycans controls thymocyte-major histocompatibility complex class I interaction . J. Biol. Chem. . 278 . 9 . 7240–6 . 2003 . 12459555 . 10.1074/jbc.M210468200 . free .
• Strausberg RL, Feingold EA, Grouse LH, etal . Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences . Proc. Natl. Acad. Sci. U.S.A. . 99 . 26 . 16899–903 . 2003 . 12477932 . 10.1073/pnas.242603899 . 139241 . 2002PNAS...9916899M . free .
• Taniguchi A, Hioki M, Matsumoto K . Transcriptional regulation of human Galbeta1,3GalNAc/Galbeta1, 4GlcNAc alpha2,3-sialyltransferase (hST3Gal IV) gene in testis and ovary cell lines . Biochem. Biophys. Res. Commun. . 301 . 3 . 764–8 . 2003 . 12565846 . 10.1016/S0006-291X(03)00041-X .
• Ota T, Suzuki Y, Nishikawa T, etal . Complete sequencing and characterization of 21,243 full-length human cDNAs . Nat. Genet. . 36 . 1 . 40–5 . 2004 . 14702039 . 10.1038/ng1285 . free .
• Gerhard DS, Wagner L, Feingold EA, etal . The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC) . Genome Res. . 14 . 10B . 2121–7 . 2004 . 15489334 . 10.1101/gr.2596504 . 528928 .
• Higai K, Miyazaki N, Azuma Y, Matsumoto K . Interleukin-1beta induces sialyl Lewis X on hepatocellular carcinoma HuH-7 cells via enhanced expression of ST3Gal IV and FUT VI gene . FEBS Lett. . 580 . 26 . 6069–75 . 2007 . 17054948 . 10.1016/j.febslet.2006.09.073 . 9731951 .
• Szabo R, Skropeta D, etal . Advancement of Sialyltransferase Inhibitors: Therapeutic Challenges and Opportunities. . Med. Res. Rev. . 37 . 2 . 210–270 . 2017 . 10.1002/med.21407 . 27678392. 26280291 .

Notes and References

1. Kitagawa H, Mattei MG, Paulson JC . Genomic organization and chromosomal mapping of the Gal beta 1,3GalNAc/Gal beta 1,4GlcNAc alpha 2,3-sialyltransferase . J Biol Chem . 271 . 2 . 931–8 . Feb 1996 . 8557707 . 10.1074/jbc.271.2.931 . free .
2. Kitagawa H, Paulson JC . Cloning of a novel alpha 2,3-sialyltransferase that sialylates glycoprotein and glycolipid carbohydrate groups . J Biol Chem . 269 . 2 . 1394–401 . Feb 1994 . 10.1016/S0021-9258(17)42271-X . 8288606 . free .
3. Web site: Entrez Gene: ST3GAL4 ST3 beta-galactoside alpha-2,3-sialyltransferase 4.