| State: | FL |
| Type: | SR |
| Route: | 349 |
| Length Mi: | 24.253 |
| Length Round: | 3 |
| Map Custom: | yes |
| Map Notes: | SR 349 in red, CR 349 in blue |
| Direction A: | South |
| Direction B: | North |
| Terminus A: | in Old Town |
| Terminus B: | near Branford |
| Counties: | Dixie, Lafayette |
| Previous Type: | SR |
| Previous Route: | 345 |
| Next Type: | SR |
| Next Route: | 359A |
State Road 349 (SR 349) is a two-lane state highway in eastern Dixie and Lafayette counties, near the Suwannee River. It is 24miles long. Near Fletcher, it intersects County Road 351 (CR 351), a major access road to Cross City and Horseshoe Beach. The northern terminus at the intersection of U.S. Highway 27 (US 27) in Grady, which is on the west side of the Suwannee River near Branford. The southern terminus of SR 349 is at an intersection of US 19/US 27 Alternate/US 98 in Old Town, although it extends southward to Suwannee as CR 349.
SR 349 was part of US 129 from 1948 to 1959,[1] and US 129 Alternate from 1959 to 1970.[2]