SPRR2A explained

Small proline-rich protein 2A is a protein that in humans is encoded by the SPRR2A gene.^{[1] [2]}

Further reading

• Gregory SG, Barlow KF, McLay KE, etal . The DNA sequence and biological annotation of human chromosome 1. . Nature . 441 . 7091 . 315–21 . 2006 . 16710414 . 10.1038/nature04727 . 2006Natur.441..315G . free .
• Tong L, Corrales RM, Chen Z, etal . Expression and Regulation of Cornified Envelope Proteins in Human Corneal Epithelium . Invest. Ophthalmol. Vis. Sci. . 47 . 5 . 1938–46 . 2006 . 16639001 . 2906387 . 10.1167/iovs.05-1129 .
• Gerhard DS, Wagner L, Feingold EA, etal . The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC) . Genome Res. . 14 . 10B . 2121–7 . 2004 . 15489334 . 10.1101/gr.2596504 . 528928 .
• Hong SH, Nah HY, Lee JY, etal . Estrogen regulates the expression of the small proline-rich 2 gene family in the mouse uterus . Mol. Cells . 17 . 3 . 477–84 . 2004 . 10.1016/S1016-8478(23)13069-X . 15232223 . free .
• Cabral A, Fischer DF, Vermeij WP, Backendorf C . Distinct functional interactions of human Skn-1 isoforms with Ese-1 during keratinocyte terminal differentiation . J. Biol. Chem. . 278 . 20 . 17792–9 . 2003 . 12624109 . 10.1074/jbc.M300508200 . free . 1887/50054 . free .
• Strausberg RL, Feingold EA, Grouse LH, etal . Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences . Proc. Natl. Acad. Sci. U.S.A. . 99 . 26 . 16899–903 . 2003 . 12477932 . 10.1073/pnas.242603899 . 139241 . 2002PNAS...9916899M . free .
• Dias Neto E, Correa RG, Verjovski-Almeida S, etal . Shotgun sequencing of the human transcriptome with ORF expressed sequence tags . Proc. Natl. Acad. Sci. U.S.A. . 97 . 7 . 3491–6 . 2000 . 10737800 . 10.1073/pnas.97.7.3491 . 16267 . 2000PNAS...97.3491D . free .
• Fischer DF, van Drunen CM, Winkler GS, etal . Involvement of a nuclear matrix association region in the regulation of the SPRR2A keratinocyte terminal differentiation marker . Nucleic Acids Res. . 26 . 23 . 5288–94 . 1999 . 9826750 . 10.1093/nar/26.23.5288 . 147987 .
• Steinert PM, Marekov LN . Direct evidence that involucrin is a major early isopeptide cross-linked component of the keratinocyte cornified cell envelope . J. Biol. Chem. . 272 . 3 . 2021–30 . 1997 . 8999895 . 10.1074/jbc.272.3.2021 . free .
• Fischer DF, Gibbs S, van De Putte P, Backendorf C . Interdependent transcription control elements regulate the expression of the SPRR2A gene during keratinocyte terminal differentiation . Mol. Cell. Biol. . 16 . 10 . 5365–74 . 1996 . 8816448 . 10.1128/MCB.16.10.5365. 231535 .
• Gibbs S, Lohman F, Teubel W, etal . Characterization of the human spr2 promoter: induction after UV irradiation or TPA treatment and regulation during differentiation of cultured primary keratinocytes . Nucleic Acids Res. . 18 . 15 . 4401–7 . 1990 . 2388825 . 10.1093/nar/18.15.4401 . 331257 .

Notes and References

1. Gibbs S, Fijneman R, Wiegant J, van Kessel AG, van De Putte P, Backendorf C . Molecular characterization and evolution of the SPRR family of keratinocyte differentiation markers encoding small proline-rich proteins . Genomics . 16 . 3 . 630–7 . Aug 1993 . 8325635 . 10.1006/geno.1993.1240 .
2. Web site: Entrez Gene: SPRR2A small proline-rich protein 2A.