SPIN1 explained

Spindlin-1 is a protein that in humans is encoded by the SPIN1 gene.^{[1] [2]}

Further reading

• Oh B, Hwang SY, Solter D, Knowles BB . Spindlin, a major maternal transcript expressed in the mouse during the transition from oocyte to embryo. . Development . 124 . 2 . 493–503 . 1997 . 10.1242/dev.124.2.493 . 9053325 .
• Hartley JL, Temple GF, Brasch MA . DNA cloning using in vitro site-specific recombination. . Genome Res. . 10 . 11 . 1788–95 . 2001 . 11076863 . 10.1101/gr.143000 . 310948 .
• Wiemann S, Weil B, Wellenreuther R, etal . Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs. . Genome Res. . 11 . 3 . 422–35 . 2001 . 11230166 . 10.1101/gr.GR1547R . 311072 .
• Simpson JC, Wellenreuther R, Poustka A, etal . Systematic subcellular localization of novel proteins identified by large-scale cDNA sequencing. . EMBO Rep. . 1 . 3 . 287–92 . 2001 . 11256614 . 10.1093/embo-reports/kvd058 . 1083732 .
• Strausberg RL, Feingold EA, Grouse LH, etal . Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. . Proc. Natl. Acad. Sci. U.S.A. . 99 . 26 . 16899–903 . 2003 . 12477932 . 10.1073/pnas.242603899 . 139241 . 2002PNAS...9916899M . free .
• Ota T, Suzuki Y, Nishikawa T, etal . Complete sequencing and characterization of 21,243 full-length human cDNAs. . Nat. Genet. . 36 . 1 . 40–5 . 2004 . 14702039 . 10.1038/ng1285 . free .
• Humphray SJ, Oliver K, Hunt AR, etal . DNA sequence and analysis of human chromosome 9. . Nature . 429 . 6990 . 369–74 . 2004 . 15164053 . 10.1038/nature02465 . 2734081 . 2004Natur.429..369H .
• Gerhard DS, Wagner L, Feingold EA, etal . The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). . Genome Res. . 14 . 10B . 2121–7 . 2004 . 15489334 . 10.1101/gr.2596504 . 528928 .
• Wiemann S, Arlt D, Huber W, etal . From ORFeome to biology: a functional genomics pipeline. . Genome Res. . 14 . 10B . 2136–44 . 2004 . 15489336 . 10.1101/gr.2576704 . 528930 .
• Mehrle A, Rosenfelder H, Schupp I, etal . The LIFEdb database in 2006. . Nucleic Acids Res. . 34 . Database issue . D415–8 . 2006 . 16381901 . 10.1093/nar/gkj139 . 1347501 .
• Jiang F, Zhao Q, Qin L, etal . Expression, purification, crystallization and preliminary X-ray analysis of human spindlin1, an ovarian cancer-related protein. . Protein Pept. Lett. . 13 . 2 . 203–5 . 2006 . 16472086 . 10.2174/092986606775101661 .
• Zhao Q, Qin L, Jiang F, etal . Structure of human spindlin1. Tandem tudor-like domains for cell cycle regulation. . J. Biol. Chem. . 282 . 1 . 647–56 . 2007 . 17082182 . 10.1074/jbc.M604029200 . free.

Notes and References

1. Gao Y, Yue W, Zhang P, Li L, Xie X, Yuan H, Chen L, Liu D, Yan F, Pei X . Spindlin1, a novel nuclear protein with a role in the transformation of NIH3T3 cells . Biochem Biophys Res Commun . 335 . 2 . 343–50 . Aug 2005 . 16098913 . 10.1016/j.bbrc.2005.07.087 . 44944387 .
2. Web site: Entrez Gene: SPIN1 spindlin 1.