SPACA3 explained
Sperm acrosome membrane-associated protein 3 is a protein that in humans is encoded by the SPACA3 gene. It may be involved in adhesion to the egg before the egg is fertilized.[1] [2]
See also
Further reading
- Niyonsaba F, Ogawa H . Protective roles of the skin against infection: implication of naturally occurring human antimicrobial agents beta-defensins, cathelicidin LL-37 and lysozyme. . J. Dermatol. Sci. . 40 . 3 . 157–68 . 2006 . 16150577 . 10.1016/j.jdermsci.2005.07.009 .
- Cramer EM, Breton-Gorius J . Ultrastructural localization of lysozyme in human neutrophils by immunogold. . J. Leukoc. Biol. . 41 . 3 . 242–7 . 1987 . 3470418 . 10.1002/jlb.41.3.242. 32012371 .
- Welsh IR, Spitznagel JK . Distribution of lysosomal enzymes, cationic proteins, and bactericidal substances in subcellular fractions of human polymorphonuclear leukocytes. . Infect. Immun. . 4 . 2 . 97–102 . 1973 . 5154881 . 10.1128/IAI.4.2.97-102.1971. 416271 .
- Ibrahim HR, Matsuzaki T, Aoki T . Genetic evidence that antibacterial activity of lysozyme is independent of its catalytic function. . FEBS Lett. . 506 . 1 . 27–32 . 2001 . 11591365 . 10.1016/S0014-5793(01)02872-1 . 21593262 .
- Strausberg RL, Feingold EA, Grouse LH, etal . Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. . Proc. Natl. Acad. Sci. U.S.A. . 99 . 26 . 16899–903 . 2003 . 12477932 . 10.1073/pnas.242603899 . 139241 . 2002PNAS...9916899M . free .
- Clark HF, Gurney AL, Abaya E, etal . The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. . Genome Res. . 13 . 10 . 2265–70 . 2003 . 12975309 . 10.1101/gr.1293003 . 403697 .
- Wang Z, Zhang Y, Mandal A, etal . The spermatozoa protein, SLLP1, is a novel cancer-testis antigen in hematologic malignancies. . Clin. Cancer Res. . 10 . 19 . 6544–50 . 2005 . 15475442 . 10.1158/1078-0432.CCR-04-0911 . free .
- Gerhard DS, Wagner L, Feingold EA, etal . The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). . Genome Res. . 14 . 10B . 2121–7 . 2004 . 15489334 . 10.1101/gr.2596504 . 528928 .
- Zhang K, Gao R, Zhang H, etal . Molecular cloning and characterization of three novel lysozyme-like genes, predominantly expressed in the male reproductive system of humans, belonging to the c-type lysozyme/alpha-lactalbumin family. . Biol. Reprod. . 73 . 5 . 1064–71 . 2006 . 16014814 . 10.1095/biolreprod.105.041889 . 21603980 . free .
Notes and References
- Mandal A, Klotz KL, Shetty J, Jayes FL, Wolkowicz MJ, Bolling LC, Coonrod SA, Black MB, Diekman AB, Haystead TA, Flickinger CJ, Herr JC . SLLP1, a unique, intra-acrosomal, non-bacteriolytic, c lysozyme-like protein of human spermatozoa . Biol Reprod . 68 . 5 . 1525–37 . Apr 2003 . 12606493 . 10.1095/biolreprod.102.010108 . free .
- Web site: Entrez Gene: SPACA3 sperm acrosome associated 3.
