SORD explained

Sorbitol dehydrogenase is an enzyme that in humans is encoded by the SORD gene.^{[1] [2]}

Further reading

• El-Kabbani O, Darmanin C, Chung RP . Sorbitol dehydrogenase: structure, function and ligand design. . Curr. Med. Chem. . 11 . 4 . 465–76 . 2004 . 14965227 . 10.2174/0929867043455927 .
• Karlsson C, Maret W, Auld DS, etal . Variability within mammalian sorbitol dehydrogenases. The primary structure of the human liver enzyme. . Eur. J. Biochem. . 186 . 3 . 543–50 . 1990 . 2691249 . 10.1111/j.1432-1033.1989.tb15240.x .
• Samanta BK, Chandra NC, Ghosh S, Mukherjee KL . Aldose metabolism in developing human fetal brain and liver. . Experientia . 40 . 12 . 1420–2 . 1985 . 6439573 . 10.1007/BF01951922 . 2545958 .
• Lee FK, Lee AY, Lin CX, etal . Cloning, sequencing, and determination of the sites of expression of mouse sorbitol dehydrogenase cDNA. . Eur. J. Biochem. . 230 . 3 . 1059–65 . 1995 . 7601136 . 10.1111/j.1432-1033.1995.tb20656.x .
• Lee FK, Cheung MC, Chung S . The human sorbitol dehydrogenase gene: cDNA cloning, sequence determination, and mapping by fluorescence in situ hybridization. . Genomics . 21 . 2 . 354–8 . 1994 . 8088829 . 10.1006/geno.1994.1276 .
• Alvarez A, Martínez A, Ibarra B, etal . Membrane-bound sorbitol dehydrogenase in human red blood cells. Studies in normal subjects and in enzyme-deficient subjects with congenital cataracts. . J. Inherit. Metab. Dis. . 16 . 1 . 67–72 . 1993 . 8487505 . 10.1007/BF00711317 . 6783099 .
• Carr IM, Markham AF, Coletta PL . Identification and characterisation of a sequence related to human sorbitol dehydrogenase. . Eur. J. Biochem. . 245 . 3 . 760–7 . 1997 . 9183016 . 10.1111/j.1432-1033.1997.00760.x . free .
• Carr IM, Whitehouse A, Coletta PL, Markham AF . Structural and evolutionary characterization of the human sorbitol dehydrogenase gene duplication. . Mamm. Genome . 9 . 12 . 1042–8 . 1999 . 9880675 . 10.1007/s003359900922 . 21773145 .
• Strausberg RL, Feingold EA, Grouse LH, etal . Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. . Proc. Natl. Acad. Sci. U.S.A. . 99 . 26 . 16899–903 . 2003 . 12477932 . 10.1073/pnas.242603899 . 139241 . 2002PNAS...9916899M . free .
• Darmanin C, Iwata T, Carper DA, etal . Expression, purification and preliminary crystallographic analysis of human sorbitol dehydrogenase. . Acta Crystallogr. D . 59 . Pt 3 . 558–60 . 2003 . 12595725 . 10.1107/S0907444903000441 .
• Gevaert K, Goethals M, Martens L, etal . Exploring proteomes and analyzing protein processing by mass spectrometric identification of sorted N-terminal peptides. . Nat. Biotechnol. . 21 . 5 . 566–9 . 2004 . 12665801 . 10.1038/nbt810 . 23783563 .
• Pauly TA, Ekstrom JL, Beebe DA, etal . X-ray crystallographic and kinetic studies of human sorbitol dehydrogenase. . Structure . 11 . 9 . 1071–85 . 2004 . 12962626 . 10.1016/S0969-2126(03)00167-9 . free .
• Gerhard DS, Wagner L, Feingold EA, etal . The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). . Genome Res. . 14 . 10B . 2121–7 . 2004 . 15489334 . 10.1101/gr.2596504 . 528928 .
• Pope SN, Lee IR . Yeast two-hybrid identification of prostatic proteins interacting with human sex hormone-binding globulin. . J. Steroid Biochem. Mol. Biol. . 94 . 1–3 . 203–8 . 2005 . 15862967 . 10.1016/j.jsbmb.2005.01.007 . 9746088 .
• Rual JF, Venkatesan K, Hao T, etal . Towards a proteome-scale map of the human protein-protein interaction network . Nature . 437 . 7062 . 1173–8 . 2005 . 16189514 . 10.1038/nature04209 . 2024-04-27 . 2005Natur.437.1173R . 4427026 .
• Klimacek M, Hellmer H, Nidetzky B . Catalytic mechanism of Zn2+-dependent polyol dehydrogenases: kinetic comparison of sheep liver sorbitol dehydrogenase with wild-type and Glu154-->Cys forms of yeast xylitol dehydrogenase . Biochem. J. . 404 . 3 . 421–9 . 2007 . 17343568 . 10.1042/BJ20061384 . 1896283 .

Notes and References

1. Iwata T, Popescu NC, Zimonjic DB, Karlsson C, Hoog JO, Vaca G, Rodriguez IR, Carper D . Structural organization of the human sorbitol dehydrogenase gene (SORD) . Genomics . 26 . 1 . 55–62 . Jul 1995 . 7782086 . 10.1016/0888-7543(95)80082-W .
2. Web site: Entrez Gene: SORD sorbitol dehydrogenase.