SOFA score explained

SOFA score
Purpose:determine rate of organ failure

The sequential organ failure assessment score (SOFA score), previously known as the sepsis-related organ failure assessment score,[1] is used to track a person's status during the stay in an intensive care unit (ICU) to determine the extent of a person's organ function or rate of failure.[2] [3] [4] [5] [6] The score is based on six different scores, one each for the respiratory, cardiovascular, hepatic, coagulation, renal and neurological systems.

The score tables below only describe points-giving conditions. In cases where the physiological parameters do not match any row, zero points are given. In cases where the physiological parameters match more than one row, the row with most points is picked.

The quick SOFA score (qSOFA) assists health care providers in estimating the risk of morbidity and mortality due to sepsis.[7]

Medical use

The SOFA scoring system is useful in predicting the clinical outcomes of critically ill patients.[8] According to an observational study at an Intensive Care Unit (ICU) in Belgium, the mortality rate is at least 50% when the score is increased, regardless of initial score, in the first 96 hours of admission, 27% to 35% if the score remains unchanged, and less than 27% if the score is reduced.[9] Score ranges from 0 (best) to 24 (worst) points.[10]

Notes and References

  1. Singer . etal . Mervyn . The Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3) . JAMA . 315 . 8 . 801–10 . en . 10.1001/jama.2016.0287 . 26903338 . 4968574 . 23 February 2016.
  2. Vincent JL, Moreno R, Takala J, Willatts S, De Mendonça A, Bruining H, Reinhart CK, Suter PM, Thijs LG . Jul 1996 . The SOFA (Sepsis-related Organ Failure Assessment) score to describe organ dysfunction/failure. On behalf of the Working Group on Sepsis-Related Problems of the European Society of Intensive Care Medicine . Intensive Care Med . 22 . 7. 707–10 . 8844239 . 10.1007/bf01709751. 40396839 .
  3. Vincent JL, de Mendonça A, Cantraine F, Moreno R, Takala J, Suter PM, Sprung CL, Colardyn F, Blecher S . Nov 1998 . Use of the SOFA score to assess the incidence of organ dysfunction/failure in intensive care units: results of a multicenter, prospective study. Working group on "sepsis-related problems" of the European Society of Intensive Care Medicine . Crit Care Med . 26 . 11. 1793–800 . 9824069 . 10.1097/00003246-199811000-00016. 28070236 .
  4. Moreno R, Vincent JL, Matos R, Mendonça A, Cantraine F, Thijs L, Takala J, Sprung C, Antonelli M, Bruining H, Willatts S . Jul 1999 . The use of maximum SOFA score to quantify organ dysfunction/failure in intensive care. Results of a prospective, multicentre study. Working Group on Sepsis related Problems of the ESICM . Intensive Care Med . 25 . 7. 686–96 . 10470572 . 10.1007/s001340050931. 34510892 .
  5. de Mendonça A, Vincent JL, Suter PM, Moreno R, Dearden NM, Antonelli M, Takala J, Sprung C, Cantraine F . Jul 2000 . Acute renal failure in the ICU: risk factors and outcome evaluated by the SOFA score . Intensive Care Med . 26 . 7. 915–21 . 10990106 . 10.1007/s001340051281. 24304874 .
  6. Ferreira FL, Bota DP, Bross A, Mélot C, Vincent JL . Oct 2001 . Serial evaluation of the SOFA score to predict outcome in critically ill patients . JAMA . 286 . 14. 1754–8 . 11594901 . 10.1001/jama.286.14.1754. free .
  7. Web site: National Inpatient Hospital Costs: The Most Expensive Conditions by Payer, 2013. www.hcup-us.ahrq.gov. Agency for Healthcare Research and Quality. Rockville, MD. 2017-01-07.
  8. Vincent. JL. de Mendonca. A. Cantraine. F. Monero. R. Takala. J. Suter. PM. Sprung. CL. Use of the SOFA score to assess the incidence of organ dysfunction/failure in intensive care units: results of a multicenter, prospective study. Working group on "sepsis-related problems" of the European Society of Intensive Care Medicine.. Critical Care Medicine. November 1998. 26. 11. 1793–800. 9824069. 10.1097/00003246-199811000-00016. 28070236.
  9. Ferreira. FL. Bota. DP. Bross. A. Melot. C. Vincent. JL. Serial evaluation of the SOFA score to predict outcome in critically ill patients.. Journal of the American Medical Association. 10 October 2001. 286. 14. 1754–1758. 11594901. 10.1001/jama.286.14.1754. free.
  10. Raith. Eamon P.. Udy. Andrew A.. Bailey. Michael. McGloughlin. Steven. MacIsaac. Christopher. Bellomo. Rinaldo. Pilcher. David V.. for the Australian and New Zealand Intensive Care Society (ANZICS) Centre for Outcomes and Resource Evaluation (CORE). 2017-01-17. Prognostic Accuracy of the SOFA Score, SIRS Criteria, and qSOFA Score for In-Hospital Mortality Among Adults With Suspected Infection Admitted to the Intensive Care Unit. JAMA. en. 317. 3. 290–300. 10.1001/jama.2016.20328. 28114553. 205078408. 0098-7484.
  11. Angus. Derek C.. Seymour. Christopher W.. Coopersmith. Craig M.. Deutschman. Clifford S.. Klompas. Michael. Levy. Mitchell M.. Martin. Gregory S.. Osborn. Tiffany M.. Rhee. Chanu. A Framework for the Development and Interpretation of Different Sepsis Definitions and Clinical Criteria. Critical Care Medicine. 44. 3. e113–e121. 10.1097/ccm.0000000000001730. 4765912. 26901559. 2016.
  12. Web site: qSOFA :: What is qSOFA?. www.qsofa.org. 2016-05-29.
  13. Fernando. Shannon M.. Tran. Alexandre. Taljaard. Monica. Cheng. Wei. Rochwerg. Bram. Seely. Andrew J.E.. Perry. Jeffrey J.. Prognostic Accuracy of the Quick Sequential Organ Failure Assessment for Mortality in Patients With Suspected Infection. Annals of Internal Medicine. 6 February 2018. 168. 4. 266–275. 10.7326/M17-2820. 29404582. 3441582.
  14. Web site: Norse . Ashley . Guirgis . Faheem . Updates and Controversies in the Early Management of Sepsis and Septic Shock EB Medicine . www.ebmedicine.net . EBMedicine . en.
  15. Web site: Hour-1 Bundle . Surviving Sepsis Campaign . Society of Critical Care Medicine and the European Society of Intensive Care Medicine.
  16. Ko . BS . Choi . SH . Shin . TG . Kim . K . Jo . YH . Ryoo . SM . Park . YS . Kwon . WY . Choi . HS . Chung . SP . Suh . GJ . Kang . H . Lim . TH . Son . D . Kim . WY . Impact of 1-Hour Bundle Achievement in Septic Shock. . Journal of Clinical Medicine . 2 February 2021 . 10 . 3 . 527 . 10.3390/jcm10030527 . 33540513. 7867161 . free .

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