Small nuclear ribonucleoprotein polypeptide E explained

Small nuclear ribonucleoprotein E is a protein that in humans is encoded by the SNRPE gene.^{[1] [2] [3]}

Interactions

Small nuclear ribonucleoprotein polypeptide E has been shown to interact with DDX20^[4] and Small nuclear ribonucleoprotein polypeptide F.^[5]

Further reading

• Sauterer RA, Goyal A, Zieve GW . Cytoplasmic assembly of small nuclear ribonucleoprotein particles from 6 S and 20 S RNA-free intermediates in L929 mouse fibroblasts . The Journal of Biological Chemistry . 265 . 2 . 1048–58 . January 1990 . 10.1016/S0021-9258(19)40157-9 . 1688550 . free .
• Stanford DR, Rohleder A, Neiswanger K, Wieben ED . DNA sequence of a human Sm autoimmune antigen. The multigene family contains a processed pseudogene . The Journal of Biological Chemistry . 262 . 21 . 9931–4 . July 1987 . 10.1016/S0021-9258(18)61052-X . 2440864 . free .
• Feeney RJ, Sauterer RA, Feeney JL, Zieve GW . Cytoplasmic assembly and nuclear accumulation of mature small nuclear ribonucleoprotein particles . The Journal of Biological Chemistry . 264 . 10 . 5776–83 . April 1989 . 10.1016/S0021-9258(18)83617-1 . 2522439 . free .
• Stanford DR, Perry CA, Holicky EL, Rohleder AM, Wieben ED . The small nuclear ribonucleoprotein E protein gene contains four introns and has upstream similarities to genes for ribosomal proteins . The Journal of Biological Chemistry . 263 . 33 . 17772–9 . November 1988 . 10.1016/S0021-9258(19)77902-2 . 2972723 . free .
• Stanford DR, Kehl M, Perry CA, Holicky EL, Harvey SE, Rohleder AM, Rehder K, Luhrmann R, Wieben ED . The complete primary structure of the human snRNP E protein . Nucleic Acids Research . 16 . 22 . 10593–605 . November 1988 . 2974536 . 338926 . 10.1093/nar/16.22.10593 .
• Woppmann A, Rinke J, Lührmann R . Direct cross-linking of snRNP proteins F and 70K to snRNAs by ultra-violet radiation in situ . Nucleic Acids Research . 16 . 23 . 10985–1004 . December 1988 . 2974540 . 338992 . 10.1093/nar/16.23.10985 .
• Kamiyama T, Aoki N, Yuasa Y . B-raf oncogene: activation by rearrangements and assignment to human chromosome 7 . Japanese Journal of Cancer Research . 84 . 3 . 250–6 . March 1993 . 8098025 . 10.1111/j.1349-7006.1993.tb02864.x . 5919149 .
• Plessel G, Lührmann R, Kastner B . Electron microscopy of assembly intermediates of the snRNP core: morphological similarities between the RNA-free (E.F.G) protein heteromer and the intact snRNP core . Journal of Molecular Biology . 265 . 2 . 87–94 . January 1997 . 9020971 . 10.1006/jmbi.1996.0713 .
• Liu Q, Fischer U, Wang F, Dreyfuss G . The spinal muscular atrophy disease gene product, SMN, and its associated protein SIP1 are in a complex with spliceosomal snRNP proteins . Cell . 90 . 6 . 1013–21 . September 1997 . 9323129 . 10.1016/S0092-8674(00)80367-0 . 10855404 . free .
• Fury MG, Zhang W, Christodoulopoulos I, Zieve GW . Multiple protein: protein interactions between the snRNP common core proteins . Experimental Cell Research . 237 . 1 . 63–9 . November 1997 . 9417867 . 10.1006/excr.1997.3750 .
• Kambach C, Walke S, Young R, Avis JM, de la Fortelle E, Raker VA, Lührmann R, Li J, Nagai K . Crystal structures of two Sm protein complexes and their implications for the assembly of the spliceosomal snRNPs . Cell . 96 . 3 . 375–87 . February 1999 . 10025403 . 10.1016/S0092-8674(00)80550-4 . 17379935 . free .
• Charroux B, Pellizzoni L, Perkinson RA, Shevchenko A, Mann M, Dreyfuss G . Gemin3: A novel DEAD box protein that interacts with SMN, the spinal muscular atrophy gene product, and is a component of gems . The Journal of Cell Biology . 147 . 6 . 1181–94 . December 1999 . 10601333 . 2168095 . 10.1083/jcb.147.6.1181 .
• Charroux B, Pellizzoni L, Perkinson RA, Yong J, Shevchenko A, Mann M, Dreyfuss G . Gemin4. A novel component of the SMN complex that is found in both gems and nucleoli . The Journal of Cell Biology . 148 . 6 . 1177–86 . March 2000 . 10725331 . 2174312 . 10.1083/jcb.148.6.1177 .
• Urlaub H, Raker VA, Kostka S, Lührmann R . Sm protein-Sm site RNA interactions within the inner ring of the spliceosomal snRNP core structure . The EMBO Journal . 20 . 1–2 . 187–96 . January 2001 . 11226169 . 140196 . 10.1093/emboj/20.1.187 .
• Gubitz AK, Mourelatos Z, Abel L, Rappsilber J, Mann M, Dreyfuss G . Gemin5, a novel WD repeat protein component of the SMN complex that binds Sm proteins . The Journal of Biological Chemistry . 277 . 7 . 5631–6 . February 2002 . 11714716 . 10.1074/jbc.M109448200 . free .
• Pellizzoni L, Baccon J, Rappsilber J, Mann M, Dreyfuss G . Purification of native survival of motor neurons complexes and identification of Gemin6 as a novel component . The Journal of Biological Chemistry . 277 . 9 . 7540–5 . March 2002 . 11748230 . 10.1074/jbc.M110141200 . free .
• Friesen WJ, Wyce A, Paushkin S, Abel L, Rappsilber J, Mann M, Dreyfuss G . A novel WD repeat protein component of the methylosome binds Sm proteins . The Journal of Biological Chemistry . 277 . 10 . 8243–7 . March 2002 . 11756452 . 10.1074/jbc.M109984200 . free .
• Jurica MS, Licklider LJ, Gygi SR, Grigorieff N, Moore MJ . Purification and characterization of native spliceosomes suitable for three-dimensional structural analysis . RNA . 8 . 4 . 426–39 . April 2002 . 11991638 . 1370266 . 10.1017/S1355838202021088 .

Notes and References

1. Fautsch MP, Wieben ED . Transcriptional regulation of the small nuclear ribonucleoprotein E protein gene. Identification of cis-acting sequences with homology to genes encoding ribosomal proteins . The Journal of Biological Chemistry . 266 . 34 . 23288–95 . December 1991 . 10.1016/S0021-9258(18)54495-1 . 1835977 . free .
2. Neiswanger K, Stanford DR, Sparkes RS, Nishimura D, Mohandas T, Klisak I, Heinzmann C, Wieben ED . Assignment of the gene for the small nuclear ribonucleoprotein E (SNRPE) to human chromosome 1q25-q43 . Genomics . 7 . 4 . 503–8 . August 1990 . 2143747 . 10.1016/0888-7543(90)90192-W .
3. Web site: Entrez Gene: SNRPE small nuclear ribonucleoprotein polypeptide E.
4. Charroux B, Pellizzoni L, Perkinson RA, Shevchenko A, Mann M, Dreyfuss G . Gemin3: A novel DEAD box protein that interacts with SMN, the spinal muscular atrophy gene product, and is a component of gems . The Journal of Cell Biology . 147 . 6 . 1181–94 . December 1999 . 10601333 . 2168095 . 10.1083/jcb.147.6.1181 .
5. Fury MG, Zhang W, Christodoulopoulos I, Zieve GW . Multiple protein: protein interactions between the snRNP common core proteins . Experimental Cell Research . 237 . 1 . 63–9 . November 1997 . 9417867 . 10.1006/excr.1997.3750 .