| Class: | Glycine transporter 1 (GlyT1) inhibitor; Glycine reuptake inhibitor |
| Synonyms: | SNG12; SNG 12; Synapsinae |
SNG-12, also known as Synapsinae, is a glycine transporter 1 (GlyT1) inhibitor, or a glycine reuptake inhibitor, which is under development for the treatment of psychotic disorders, dementia, depressive disorders, and suicidal ideation.[1] [2] [3] As of September 2022, it is in phase 3 clinical trials for depressive disorders and suicidal ideation and is in phase 2 clinical rials for psychotic disorders and dementia. The drug is under development by SyneuRx. It is described as a small molecule, but its chemical structure does not appear to have been disclosed.[4]