Y+L amino acid transporter 2 explained

Y+L amino acid transporter 2, also known as cationic amino acid transporter, y+ system, is a protein that in humans is encoded by the SLC7A6 gene.^{[1] [2]}

See also

• Heterodimeric amino acid transporter

Further reading

• Sekine Y, Nishibori Y, Akimoto Y, Kudo A, Ito N, Fukuhara D, Kurayama R, Higashihara E, Babu E, Kanai Y, Asanuma K, Nagata M, Majumdar A, Tryggvason K, Yan K . Amino acid transporter LAT3 is required for podocyte development and function . Journal of the American Society of Nephrology . 20 . 7 . 1586–96 . July 2009 . 19443642 . 2709689 . 10.1681/ASN.2008070809 .
• Suzuki Y, Yamashita R, Shirota M, Sakakibara Y, Chiba J, Mizushima-Sugano J, Nakai K, Sugano S . Sequence comparison of human and mouse genes reveals a homologous block structure in the promoter regions . Genome Research . 14 . 9 . 1711–8 . September 2004 . 15342556 . 515316 . 10.1101/gr.2435604 .
• Torrents D, Estévez R, Pineda M, Fernández E, Lloberas J, Shi YB, Zorzano A, Palacín M . Identification and characterization of a membrane protein (y+L amino acid transporter-1) that associates with 4F2hc to encode the amino acid transport activity y+L. A candidate gene for lysinuric protein intolerance . The Journal of Biological Chemistry . 273 . 49 . 32437–45 . December 1998 . 9829974 . 10.1074/jbc.273.49.32437 . free . 2445/176951 . free .
• Bröer A, Wagner CA, Lang F, Bröer S . The heterodimeric amino acid transporter 4F2hc/y+LAT2 mediates arginine efflux in exchange with glutamine . The Biochemical Journal . 349 Pt 3 . Pt 3 . 787–95 . August 2000 . 10903140 . 1221206 . 10.1042/bj3490787.
• Xu D, Hemler ME . Metabolic activation-related CD147-CD98 complex . Molecular & Cellular Proteomics . 4 . 8 . 1061–71 . August 2005 . 15901826 . 1351277 . 10.1074/mcp.M400207-MCP200 . free .

Notes and References

1. Web site: Entrez Gene: solute carrier family 7 (cationic amino acid transporter.
2. Pfeiffer R, Rossier G, Spindler B, Meier C, Kühn L, Verrey F . Amino acid transport of y+L-type by heterodimers of 4F2hc/CD98 and members of the glycoprotein-associated amino acid transporter family . The EMBO Journal . 18 . 1 . 49–57 . January 1999 . 9878049 . 1171101 . 10.1093/emboj/18.1.49 .