GDP-fucose transporter 1 explained

GDP-fucose transporter 1 is a protein that in humans is encoded by the SLC35C1 gene.^{[1] [2] [3]}

Defects can be associated with Congenital disorder of glycosylation type IIc.

See also

• Solute carrier family
• EamA

Further reading

• Maruyama K, Sugano S . Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides. . Gene . 138 . 1–2 . 171–4 . 1994 . 8125298 . 10.1016/0378-1119(94)90802-8 .
• Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, etal . Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library . Gene . 200 . 1–2 . 149–56 . 1997 . 9373149 . 10.1016/S0378-1119(97)00411-3 .
• Hidalgo A, Ma S, Peired AJ, etal . Insights into leukocyte adhesion deficiency type 2 from a novel mutation in the GDP-fucose transporter gene . Blood . 101 . 5 . 1705–12 . 2003 . 12406889 . 10.1182/blood-2002-09-2840 . free .
• Strausberg RL, Feingold EA, Grouse LH, etal . Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences . Proc. Natl. Acad. Sci. U.S.A. . 99 . 26 . 16899–903 . 2003 . 12477932 . 10.1073/pnas.242603899 . 139241 . 2002PNAS...9916899M . free .
• Ota T, Suzuki Y, Nishikawa T, etal . Complete sequencing and characterization of 21,243 full-length human cDNAs . Nat. Genet. . 36 . 1 . 40–5 . 2004 . 14702039 . 10.1038/ng1285 . free .
• Gerhard DS, Wagner L, Feingold EA, etal . The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC) . Genome Res. . 14 . 10B . 2121–7 . 2004 . 15489334 . 10.1101/gr.2596504 . 528928 .
• Helmus Y, Denecke J, Yakubenia S, etal . Leukocyte adhesion deficiency II patients with a dual defect of the GDP-fucose transporter . Blood . 107 . 10 . 3959–66 . 2006 . 16455955 . 10.1182/blood-2005-08-3334 . free .

External links

• GeneReviews/NCBI/NIH/UW entry on Congenital Disorders of Glycosylation Overview

Notes and References

1. Luhn K, Wild MK, Eckhardt M, Gerardy-Schahn R, Vestweber D . The gene defective in leukocyte adhesion deficiency II encodes a putative GDP-fucose transporter . Nat Genet . 28 . 1 . 69–72 . Apr 2001 . 11326279 . 10.1038/88289 .
2. Lubke T, Marquardt T, Etzioni A, Hartmann E, von Figura K, Korner C . Complementation cloning identifies CDG-IIc, a new type of congenital disorders of glycosylation, as a GDP-fucose transporter deficiency . Nat Genet . 28 . 1 . 73–6 . Apr 2001 . 11326280 . 10.1038/88299 .
3. Web site: Entrez Gene: SLC35C1 solute carrier family 35, member C1.