CMP-sialic acid transporter explained

CMP-sialic acid transporter is a protein that in humans is encoded by the SLC35A1 gene.^{[1] [2] [3]}

See also

• Solute carrier family

Further reading

• Wahlberg JE . Sensitization and testing of guinea pigs with nickel sulfate. . Dermatologica . 152 . 6 . 321–30 . 1976 . 964426 . 10.1159/000251278.
• Harvey BE, Thomas P . Inhibition of CMP-sialic acid transport in human liver and colorectal cancer cell lines by a sialic acid nucleoside conjugate (KI-8110). . Biochem. Biophys. Res. Commun. . 190 . 2 . 571–5 . 1993 . 8427599 . 10.1006/bbrc.1993.1086 .
• Lennon G, Auffray C, Polymeropoulos M, Soares MB . The I.M.A.G.E. Consortium: an integrated molecular analysis of genomes and their expression. . Genomics . 33 . 1 . 151–2 . 1996 . 8617505 . 10.1006/geno.1996.0177 . free .
• Strausberg RL, Feingold EA, Grouse LH, etal . Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. . Proc. Natl. Acad. Sci. U.S.A. . 99 . 26 . 16899–903 . 2003 . 12477932 . 10.1073/pnas.242603899 . 139241. 2002PNAS...9916899M . free .
• Aoki K, Ishida N, Kawakita M . Substrate recognition by nucleotide sugar transporters: further characterization of substrate recognition regions by analyses of UDP-galactose/CMP-sialic acid transporter chimeras and biochemical analysis of the substrate specificity of parental and chimeric transporters. . J. Biol. Chem. . 278 . 25 . 22887–93 . 2003 . 12682060 . 10.1074/jbc.M302620200 . free .
• Mungall AJ, Palmer SA, Sims SK, etal . The DNA sequence and analysis of human chromosome 6. . Nature . 425 . 6960 . 805–11 . 2003 . 14574404 . 10.1038/nature02055 . 2003Natur.425..805M . free .
• Ota T, Suzuki Y, Nishikawa T, etal . Complete sequencing and characterization of 21,243 full-length human cDNAs. . Nat. Genet. . 36 . 1 . 40–5 . 2004 . 14702039 . 10.1038/ng1285 . free .
• Gerhard DS, Wagner L, Feingold EA, etal . The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). . Genome Res. . 14 . 10B . 2121–7 . 2004 . 15489334 . 10.1101/gr.2596504 . 528928.
• Martinez-Duncker I, Dupré T, Piller V, etal . Genetic complementation reveals a novel human congenital disorder of glycosylation of type II, due to inactivation of the Golgi CMP-sialic acid transporter. . Blood . 105 . 7 . 2671–6 . 2005 . 15576474 . 10.1182/blood-2004-09-3509 . 13582151 . free .
• Misaki R, Fujiyama K, Seki T . Expression of human CMP-N-acetylneuraminic acid synthetase and CMP-sialic acid transporter in tobacco suspension-cultured cell. . Biochem. Biophys. Res. Commun. . 339 . 4 . 1184–9 . 2006 . 16343442 . 10.1016/j.bbrc.2005.11.130 .
• Zhao W, Chen TL, Vertel BM, Colley KJ . The CMP-sialic acid transporter is localized in the medial-trans Golgi and possesses two specific endoplasmic reticulum export motifs in its carboxyl-terminal cytoplasmic tail. . J. Biol. Chem. . 281 . 41 . 31106–18 . 2006 . 16923816 . 10.1074/jbc.M605564200 . free .

External links

• GeneReviews/NCBI/NIH/UW entry on Congenital Disorders of Glycosylation Overview

Notes and References

1. Ishida N, Miura N, Yoshioka S, Kawakita M . Molecular cloning and characterization of a novel isoform of the human UDP-galactose transporter, and of related complementary DNAs belonging to the nucleotide-sugar transporter gene family . J Biochem . 120 . 6 . 1074–8 . Apr 1997 . 9010752 . 10.1093/oxfordjournals.jbchem.a021523.
2. Ishida N, Ito M, Yoshioka S, Sun-Wada GH, Kawakita M . Functional expression of human golgi CMP-sialic acid transporter in the Golgi complex of a transporter-deficient Chinese hamster ovary cell mutant . J Biochem . 124 . 1 . 171–8 . Sep 1998 . 9644260 . 10.1093/oxfordjournals.jbchem.a022076.
3. Web site: Entrez Gene: SLC35A1 solute carrier family 35 (CMP-sialic acid transporter), member A1.