SLC2A7 explained

Solute carrier family 2, facilitated glucose transporter member 7 also known as glucose transporter 7 (GLUT7) is a protein that in humans is encoded by the SLC2A7 gene.^[1]

SLC2A7 belongs to a family of transporters that catalyze the uptake of sugars through facilitated diffusion.^[2] This family of transporters shows conservation of 12 transmembrane helices as well as functionally significant amino acid residues.^[3]

See also

• Glucose transporter

Further reading

• Manolescu A, Salas-Burgos AM, Fischbarg J, Cheeseman CI . Identification of a hydrophobic residue as a key determinant of fructose transport by the facilitative hexose transporter SLC2A7 (GLUT7). . J. Biol. Chem. . 280 . 52 . 42978–83 . 2005 . 16186102 . 10.1074/jbc.M508678200 . free .

Notes and References

1. Web site: Entrez Gene: solute carrier family 2 (facilitated glucose transporter).
2. Li Q, Manolescu A, Ritzel M, Yao S, Slugoski M, Young JD, Chen XZ, Cheeseman CI . Cloning and functional characterization of the human GLUT7 isoform SLC2A7 from the small intestine . Am. J. Physiol. Gastrointest. Liver Physiol. . 287 . 1 . G236–42 . July 2004 . 15033637 . 10.1152/ajpgi.00396.2003 . 21269350 .
3. Joost HG, Thorens B . The extended GLUT-family of sugar/polyol transport facilitators: nomenclature, sequence characteristics, and potential function of its novel members (review) . Mol. Membr. Biol. . 18 . 4 . 247–56 . 2001 . 11780753 . 10.1080/09687680110090456. 22667943 . free .