SLC12A8 explained
Solute carrier family 12 member 8 (SLC12A8), also known as cation-chloride cotransporter 9 (CCC9), is a protein that in humans is encoded by the SLC12A8 gene.[1] [2]
Further reading
- Kimura K, Wakamatsu A, Suzuki Y, Ota T, Nishikawa T, Yamashita R, Yamamoto J, Sekine M, Tsuritani K, Wakaguri H, Ishii S, Sugiyama T, Saito K, Isono Y, Irie R, Kushida N, Yoneyama T, Otsuka R, Kanda K, Yokoi T, Kondo H, Wagatsuma M, Murakawa K, Ishida S, Ishibashi T, Takahashi-Fujii A, Tanase T, Nagai K, Kikuchi H, Nakai K, Isogai T, Sugano S . Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes . Genome Research . 16 . 1 . 55–65 . January 2006 . 16344560 . 1356129 . 10.1101/gr.4039406 .
- Adams MD, Kerlavage AR, Fleischmann RD, Fuldner RA, Bult CJ, Lee NH, Kirkness EF, Weinstock KG, Gocayne JD, White O . Initial assessment of human gene diversity and expression patterns based upon 83 million nucleotides of cDNA sequence . Nature . 377 . 6547 Suppl . 3–174 . September 1995 . 7566098 .
- Daigle ND, Carpentier GA, Frenette-Cotton R, Simard MG, Lefoll MH, Noël M, Caron L, Noël J, Isenring P . Molecular characterization of a human cation-Cl- cotransporter (SLC12A8A, CCC9A) that promotes polyamine and amino acid transport . Journal of Cellular Physiology . 220 . 3 . 680–9 . September 2009 . 19472210 . 10.1002/jcp.21814 . 28766587 .
- Hebert SC, Mount DB, Gamba G . Molecular physiology of cation-coupled Cl- cotransport: the SLC12 family . Pflügers Archiv . 447 . 5 . 580–93 . February 2004 . 12739168 . 10.1007/s00424-003-1066-3 . 21998913 .
- Hüffmeier U, Lascorz J, Traupe H, Böhm B, Schürmeier-Horst F, Ständer M, Kelsch R, Baumann C, Küster W, Burkhardt H, Reis A . Systematic linkage disequilibrium analysis of SLC12A8 at PSORS5 confirms a role in susceptibility to psoriasis vulgaris . The Journal of Investigative Dermatology . 125 . 5 . 906–12 . November 2005 . 16297188 . 10.1111/j.0022-202X.2005.23847.x . free .
Notes and References
- Web site: Entrez Gene: solute carrier family 12 (potassium/chloride transporters).
- Hewett D, Samuelsson L, Polding J, Enlund F, Smart D, Cantone K, See CG, Chadha S, Inerot A, Enerback C, Montgomery D, Christodolou C, Robinson P, Matthews P, Plumpton M, Wahlstrom J, Swanbeck G, Martinsson T, Roses A, Riley J, Purvis I . Identification of a psoriasis susceptibility candidate gene by linkage disequilibrium mapping with a localized single nucleotide polymorphism map . Genomics . 79 . 3 . 305–14 . March 2002 . 11863360 . 10.1006/geno.2002.6720 .