SLC12A7 explained

Solute carrier family 12 member 7 is a protein that in humans is encoded by the SLC12A7 gene.^{[1] [2]}

See also

• Solute carrier family
• cotransporter

Further reading

• Mercado A, Song L, Vazquez N, Mount DB, Gamba G . Functional comparison of the K+-Cl- cotransporters KCC1 and KCC4 . The Journal of Biological Chemistry . 275 . 39 . 30326–34 . September 2000 . 10913127 . 10.1074/jbc.M003112200 . free .
• Hattori A, Okumura K, Nagase T, Kikuno R, Hirosawa M, Ohara O . Characterization of long cDNA clones from human adult spleen . DNA Research . 7 . 6 . 357–66 . December 2000 . 11214971 . 10.1093/dnares/7.6.357 . free .
• Boettger T, Hübner CA, Maier H, Rust MB, Beck FX, Jentsch TJ . Deafness and renal tubular acidosis in mice lacking the K-Cl co-transporter Kcc4 . Nature . 416 . 6883 . 874–8 . April 2002 . 11976689 . 10.1038/416874a . 2002Natur.416..874B . 4389928 .
• Bräuer M, Frei E, Claes L, Grissmer S, Jäger H . Influence of K-Cl cotransporter activity on activation of volume-sensitive Cl- channels in human osteoblasts . American Journal of Physiology. Cell Physiology . 285 . 1 . C22-30 . July 2003 . 12637262 . 10.1152/ajpcell.00289.2002 .
• Karadsheh MF, Byun N, Mount DB, Delpire E . Localization of the KCC4 potassium-chloride cotransporter in the nervous system . Neuroscience . 123 . 2 . 381–91 . 2004 . 14698746 . 10.1016/j.neuroscience.2003.10.004 . 41970238 .
• Shen MR, Lin AC, Hsu YM, Chang TJ, Tang MJ, Alper SL, Ellory JC, Chou CY . Insulin-like growth factor 1 stimulates KCl cotransport, which is necessary for invasion and proliferation of cervical cancer and ovarian cancer cells . The Journal of Biological Chemistry . 279 . 38 . 40017–25 . September 2004 . 15262997 . 10.1074/jbc.M406706200 . free .
• Hsu YM, Chou CY, Chen HH, Lee WY, Chen YF, Lin PW, Alper SL, Ellory JC, Shen MR . IGF-1 upregulates electroneutral K-Cl cotransporter KCC3 and KCC4 which are differentially required for breast cancer cell proliferation and invasiveness . Journal of Cellular Physiology . 210 . 3 . 626–36 . March 2007 . 17133354 . 10.1002/jcp.20859 . 21615465 . free .

Notes and References

1. Mount DB, Mercado A, Song L, Xu J, George AL, Delpire E, Gamba G . Cloning and characterization of KCC3 and KCC4, new members of the cation-chloride cotransporter gene family . The Journal of Biological Chemistry . 274 . 23 . 16355–62 . June 1999 . 10347194 . 10.1074/jbc.274.23.16355 . free .
2. Web site: Entrez Gene: SLC12A7 solute carrier family 12 (potassium/chloride transporters), member 7.