SKF-91488 explained

SKF-91488 is a histamine N-methyltransferase inhibitor. It prevents the degradation of histamine, leading to increased histamine levels.^{[1] [2]}

See also

• α-Fluoromethylhistidine
• Histidine methyl ester

Notes and References

1. Thakkar. Mahesh M.. Histamine in the regulation of wakefulness. Sleep Medicine Reviews. February 2011. 15. 1. 65–74. 10.1016/j.smrv.2010.06.004. 20851648. 3016451.
2. Tamaoki. J.. Chiyotani. A.. Tagaya. E.. Isono. K.. Konno. K.. Histamine N-methyltransferase Modulates Human Bronchial Smooth Muscle Contraction. Mediators of Inflammation. 1994. 3. 2. 125–129. 10.1155/S0962935194000153. 18472930. 2367027. free.