| Folded: | 2018 |
| Teams: | 14 |
| Promotion: | Super League First Division |
| Domest Cup: | Scottish Junior Cup |
| Champions: | Rossvale F.C. |
| Season: | 2017–18 |
| Website: | SJFA |
The Central District League First Division was the third-tier division of the West Region of the Scottish Junior Football Association. The two highest-placed teams at the end of the season were promoted to the Super League, First Division. The three lowest-placed teams were relegated to Central District Second Division.
It sat below region-wide division and alongside an 'Ayrshire' geographical equivalent (with one division), representing the Ayrshire League and Central League which merged to form the West Region.
In 2018, the lower leagues in the West Region were reorganised, no longer being split geographically, with the result that the Central First and Second Divisions and the Ayrshire Division merged and were separated into two tiers (League One and League Two).
| Club | Location | Home Ground | Finishing position 2015–16 | |
|---|---|---|---|---|
| Bellshill Athletic | Rockburn Park | Super League First Division, 13th | ||
| Benburb | New Tinto Park | Central District Second Division, 2nd | ||
| Cambuslang Rangers | Somervell Park | Central District Second Division, 3rd | ||
| Forth Wanderers | Kingshill Park | Central District Second Division, 1st | ||
| Greenock Juniors | Ravenscraig Stadium | Super League First Division, 11th | ||
| Johnstone Burgh | Keanie Park | 7th | ||
| Larkhall Thistle | Gasworks Park | 6th | ||
| Lesmahagow | Craighead Park | 9th | ||
| Neilston Juniors | Brig O'Lea Stadium | 11th | ||
| Rossvale | Petershill Park1 | 4th | ||
| St. Roch's | James McGrory Park | 5th | ||
| Thorniewood United | Robertson Park | 10th | ||
| Vale of Clyde | Fullarton Park | 8th | ||
| Wishaw Juniors | Beltane Park | 3rd |