SIB-1553A explained

SIB-1553A is a nicotinic acetylcholine receptor agonist that is selective for receptors with a β4 subunit. Administration of SIB-1553A improved memory and attention in a Parkinson's disease model.[1]

Notes and References

  1. Schneider. JS. The Subtype-Selective Nicotinic Acetylcholine Receptor Agonist SIB-1553A Improves Both Attention and Memory Components of a Spatial Working Memory Task in Chronic Low Dose 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine-Treated Monkeys. Journal of Pharmacology and Experimental Therapeutics. July 2003. 306. 1. 401–6. 10.1124/jpet.103.051912. 12721323. 7060934.

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