| State: | OK |
| Type: | SH |
| Route: | 144 |
| Map Custom: | yes |
| Maint: | ODOT |
| Length Mi: | 36.97 |
| Direction A: | West |
| Direction B: | East |
| Terminus A: | southeast of Clayton |
| Terminus B: | east of Octavia |
| Previous Type: | SH |
| Previous Route: | 142 |
| Next Type: | SH |
| Next Route: | 145 |
State Highway 144 (abbreviated SH-144) is a state highway in the Little Dixie region of Oklahoma, United States. It runs 36.97miles in Pushmataha and Le Flore Counties. It does not have any lettered spur routes.
SH-144 begins at US-271, nine miles (14 km) southeast of Clayton. From there it runs to the east through the community of Nashoba, and into the Kiamichi Mountains. Highway 144 parallels the Little River most of the way through the mountains, passing through Fewell, and just south of Honobia.
Highway 144 ends at US-259 in the Kiamichi Mountains, just east of Octavia.