SGPP1 explained

Sphingosine-1-phosphate phosphatase 1 is an enzyme that in humans is encoded by the SGPP1 gene.^{[1] [2]}

Further reading

• Ogawa C, Kihara A, Gokoh M, Igarashi Y . Identification and characterization of a novel human sphingosine-1-phosphate phosphohydrolase, hSPP2. . J. Biol. Chem. . 278 . 2 . 1268–72 . 2003 . 12411432 . 10.1074/jbc.M209514200 . free .
• Strausberg RL, Feingold EA, Grouse LH, etal . Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. . Proc. Natl. Acad. Sci. U.S.A. . 99 . 26 . 16899–903 . 2003 . 12477932 . 10.1073/pnas.242603899 . 139241 . free . 2002PNAS...9916899M .
• Heilig R, Eckenberg R, Petit JL, etal . The DNA sequence and analysis of human chromosome 14. . Nature . 421 . 6923 . 601–7 . 2003 . 12508121 . 10.1038/nature01348 . 2003Natur.421..601H . free .
• Johnson KR, Johnson KY, Becker KP, etal . Role of human sphingosine-1-phosphate phosphatase 1 in the regulation of intra- and extracellular sphingosine-1-phosphate levels and cell viability. . J. Biol. Chem. . 278 . 36 . 34541–7 . 2003 . 12815058 . 10.1074/jbc.M301741200 . free .
• Le Stunff H, Mikami A, Giussani P, etal . Role of sphingosine-1-phosphate phosphatase 1 in epidermal growth factor-induced chemotaxis. . J. Biol. Chem. . 279 . 33 . 34290–7 . 2004 . 15180992 . 10.1074/jbc.M404907200 . free .
• Gerhard DS, Wagner L, Feingold EA, etal . The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). . Genome Res. . 14 . 10B . 2121–7 . 2004 . 15489334 . 10.1101/gr.2596504 . 528928 .
• Giussani P, Maceyka M, Le Stunff H, etal . Sphingosine-1-phosphate phosphohydrolase regulates endoplasmic reticulum-to-golgi trafficking of ceramide. . Mol. Cell. Biol. . 26 . 13 . 5055–69 . 2006 . 16782891 . 10.1128/MCB.02107-05 . 1489178 .
• Olsen JV, Blagoev B, Gnad F, etal . Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. . Cell . 127 . 3 . 635–48 . 2006 . 17081983 . 10.1016/j.cell.2006.09.026 . free .

Notes and References

1. Mandala SM, Thornton R, Galve-Roperh I, Poulton S, Peterson C, Olivera A, Bergstrom J, Kurtz MB, Spiegel S . Molecular cloning and characterization of a lipid phosphohydrolase that degrades sphingosine-1- phosphate and induces cell death . Proc Natl Acad Sci U S A . 97 . 14 . 7859–64 . Aug 2000 . 10859351 . 16635 . 10.1073/pnas.120146897 . 2000PNAS...97.7859M . free .
2. Web site: Entrez Gene: SGPP1 sphingosine-1-phosphate phosphatase 1.