SFRS4 explained

Splicing factor, arginine/serine-rich 4 is a protein that in humans is encoded by the SFRS4 gene.^{[1] [2]}

Interactions

SFRS4 has been shown to interact with Pinin.^[3]

Further reading

• Zahler AM . Lane WS . Stolk JA . Roth MB . SR proteins: a conserved family of pre-mRNA splicing factors . Genes Dev. . 6 . 5 . 837–47 . 1992 . 1577277 . 10.1101/gad.6.5.837 . free .
• Ramchatesingh J, Zahler AM, Neugebauer KM, etal . A subset of SR proteins activates splicing of the cardiac troponin T alternative exon by direct interactions with an exonic enhancer . Mol. Cell. Biol. . 15 . 9 . 4898–907 . 1995 . 7651409 . 10.1128/MCB.15.9.4898. 230736 .
• Maruyama K . Sugano S . Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides . Gene . 138 . 1–2 . 171–4 . 1994 . 8125298 . 10.1016/0378-1119(94)90802-8 .
• Gui JF . Lane WS . Fu XD . A serine kinase regulates intracellular localization of splicing factors in the cell cycle . Nature . 369 . 6482 . 678–82 . 1994 . 8208298 . 10.1038/369678a0 . 1994Natur.369..678G . 4275539 . 2019-12-12 . 2020-12-03 . https://web.archive.org/web/20201203094718/http://ir.ihb.ac.cn/handle/152342/10318 . dead .
• Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, etal . Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library . Gene . 200 . 1–2 . 149–56 . 1997 . 9373149 . 10.1016/S0378-1119(97)00411-3 .
• Zhang WJ . Wu JY . Sip1, a Novel RS Domain-Containing Protein Essential for Pre-mRNA Splicing . Mol. Cell. Biol. . 18 . 2 . 676–84 . 1998 . 9447963 . 10.1128/MCB.18.2.676. 108778 .
• Blencowe BJ . Issner R . Nickerson JA . Sharp PA . A coactivator of pre-mRNA splicing . Genes Dev. . 12 . 7 . 996–1009 . 1998 . 9531537 . 10.1101/gad.12.7.996 . 316672 .
• Papoutsopoulou S, Nikolakaki E, Chalepakis G, etal . SR protein-specific kinase 1 is highly expressed in testis and phosphorylates protamine 1 . Nucleic Acids Res. . 27 . 14 . 2972–80 . 1999 . 10390541 . 10.1093/nar/27.14.2972 . 148514 .
• Monsalve M, Wu Z, Adelmant G, etal . Direct coupling of transcription and mRNA processing through the thermogenic coactivator PGC-1 . Mol. Cell . 6 . 2 . 307–16 . 2000 . 10983978 . 10.1016/S1097-2765(00)00031-9 . free .
• Strausberg RL, Feingold EA, Grouse LH, etal . Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences . Proc. Natl. Acad. Sci. U.S.A. . 99 . 26 . 16899–903 . 2003 . 12477932 . 10.1073/pnas.242603899 . 139241 . 2002PNAS...9916899M . free .
• Meissner M, Lopato S, Gotzmann J, etal . Proto-oncoprotein TLS/FUS is associated to the nuclear matrix and complexed with splicing factors PTB, SRm160, and SR proteins . Exp. Cell Res. . 283 . 2 . 184–95 . 2003 . 12581738 . 10.1016/S0014-4827(02)00046-0 .
• Li J, Hawkins IC, Harvey CD, etal . Regulation of Alternative Splicing by SRrp86 and Its Interacting Proteins . Mol. Cell. Biol. . 23 . 21 . 7437–47 . 2003 . 14559993 . 10.1128/MCB.23.21.7437-7447.2003 . 207616 .
• Zimowska G, Shi J, Munguba G, etal . Pinin/DRS/memA interacts with SRp75, SRm300 and SRrp130 in corneal epithelial cells . Invest. Ophthalmol. Vis. Sci. . 44 . 11 . 4715–23 . 2003 . 14578391 . 10.1167/iovs.03-0240 . free .
• de Graaf K, Hekerman P, Spelten O, etal . Characterization of cyclin L2, a novel cyclin with an arginine/serine-rich domain: phosphorylation by DYRK1A and colocalization with splicing factors . J. Biol. Chem. . 279 . 6 . 4612–24 . 2004 . 14623875 . 10.1074/jbc.M310794200 . free .
• Gerhard DS, Wagner L, Feingold EA, etal . The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC) . Genome Res. . 14 . 10B . 2121–7 . 2004 . 15489334 . 10.1101/gr.2596504 . 528928 .
• Rush J, Moritz A, Lee KA, etal . Immunoaffinity profiling of tyrosine phosphorylation in cancer cells . Nat. Biotechnol. . 23 . 1 . 94–101 . 2005 . 15592455 . 10.1038/nbt1046 . 7200157 .
• Barrios-Rodiles M, Brown KR, Ozdamar B, etal . High-throughput mapping of a dynamic signaling network in mammalian cells . Science . 307 . 5715 . 1621–5 . 2005 . 15761153 . 10.1126/science.1105776 . 2005Sci...307.1621B . 39457788 .
• Rual JF, Venkatesan K, Hao T, etal . Towards a proteome-scale map of the human protein-protein interaction network . Nature . 437 . 7062 . 1173–8 . 2005 . 16189514 . 10.1038/nature04209 . 2005Natur.437.1173R . 4427026 .
• Gregory SG, Barlow KF, McLay KE, etal . The DNA sequence and biological annotation of human chromosome 1 . Nature . 441 . 7091 . 315–21 . 2006 . 16710414 . 10.1038/nature04727 . 2006Natur.441..315G . free .

Notes and References

1. Zahler AM . Neugebauer KM . Stolk JA . Roth MB . Human SR proteins and isolation of a cDNA encoding SRp75 . Mol Cell Biol . 13 . 7 . 4023–8 . Jul 1993 . 8321209 . 359951 . 10.1128/MCB.13.7.4023.
2. Web site: Entrez Gene: SFRS4 splicing factor, arginine/serine-rich 4.
3. Zimowska . Grazyna . Shi Jia . Munguba Gustavo . Jackson Moira R . Alpatov Roman . Simmons Matthew N . Shi Yujiang . Sugrue Stephen P . Nov 2003 . Pinin/DRS/memA interacts with SRp75, SRm300 and SRrp130 in corneal epithelial cells . Invest. Ophthalmol. Vis. Sci. . 44 . 11 . 4715–23 . 0146-0404. 14578391 . 10.1167/iovs.03-0240 . free .