SFRS3 explained

Splicing factor, arginine/serine-rich 3 is a protein that in humans is encoded by the SFRS3 gene.^{[1] [2]}

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Interactions

SFRS3 has been shown to interact with RBM7.^[3]

Further reading

• Ayane M . Preuss U . Köhler G . Nielsen PJ . A differentially expressed murine RNA encoding a protein with similarities to two types of nucleic acid binding motifs. . Nucleic Acids Res. . 19 . 6 . 1273–8 . 1991 . 2030943 . 10.1093/nar/19.6.1273 . 333853 .
• Gui JF . Lane WS . Fu XD . A serine kinase regulates intracellular localization of splicing factors in the cell cycle. . Nature . 369 . 6482 . 678–82 . 1994 . 8208298 . 10.1038/369678a0 . 1994Natur.369..678G . 4275539 . 2019-12-14 . 2020-12-03 . https://web.archive.org/web/20201203094718/http://ir.ihb.ac.cn/handle/152342/10318 . dead .
• Cáceres JF . Screaton GR . Krainer AR . A specific subset of SR proteins shuttles continuously between the nucleus and the cytoplasm. . Genes Dev. . 12 . 1 . 55–66 . 1998 . 9420331 . 10.1101/gad.12.1.55 . 316398 .
• Zhang WJ . Wu JY . Sip1, a novel RS domain-containing protein essential for pre-mRNA splicing. . Mol. Cell. Biol. . 18 . 2 . 676–84 . 1998 . 9447963 . 10.1128/MCB.18.2.676. 108778 .
• Tripodis N, Mason R, Humphray SJ, etal . Physical map of human 6p21.2-6p21.3: region flanking the centromeric end of the major histocompatibility complex. . Genome Res. . 8 . 6 . 631–43 . 1999 . 9647638 . 10.1101/gr.8.6.631. 310739 .
• Papoutsopoulou S, Nikolakaki E, Chalepakis G, etal . SR protein-specific kinase 1 is highly expressed in testis and phosphorylates protamine 1. . Nucleic Acids Res. . 27 . 14 . 2972–80 . 1999 . 10390541 . 10.1093/nar/27.14.2972 . 148514 .
• Barnard DC . Patton JG . Identification and characterization of a novel serine-arginine-rich splicing regulatory protein. . Mol. Cell. Biol. . 20 . 9 . 3049–57 . 2000 . 10757789 . 10.1128/MCB.20.9.3049-3057.2000 . 85584 .
• Shnyreva M, Schullery DS, Suzuki H, etal . Interaction of two multifunctional proteins. Heterogeneous nuclear ribonucleoprotein K and Y-box-binding protein. . J. Biol. Chem. . 275 . 20 . 15498–503 . 2000 . 10809782 . 10.1074/jbc.275.20.15498 . free .
• Elliott DJ, Bourgeois CF, Klink A, etal . A mammalian germ cell-specific RNA-binding protein interacts with ubiquitously expressed proteins involved in splice site selection. . Proc. Natl. Acad. Sci. U.S.A. . 97 . 11 . 5717–22 . 2000 . 10823932 . 10.1073/pnas.97.11.5717 . 18499 . 2000PNAS...97.5717E . free .
• Huang Y . Steitz JA . Splicing factors SRp20 and 9G8 promote the nucleocytoplasmic export of mRNA. . Mol. Cell . 7 . 4 . 899–905 . 2001 . 11336712 . 10.1016/S1097-2765(01)00233-7 . free .
• Andersen JS, Lyon CE, Fox AH, etal . Directed proteomic analysis of the human nucleolus. . Curr. Biol. . 12 . 1 . 1–11 . 2002 . 11790298 . 10.1016/S0960-9822(01)00650-9 . 14132033 . free .
• Barnard DC . Li J . Peng R . Patton JG . Regulation of alternative splicing by SRrp86 through coactivation and repression of specific SR proteins. . RNA . 8 . 4 . 526–33 . 2002 . 11991645 . 10.1017/S1355838202029928 . 1370273 .
• Strausberg RL, Feingold EA, Grouse LH, etal . Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. . Proc. Natl. Acad. Sci. U.S.A. . 99 . 26 . 16899–903 . 2003 . 12477932 . 10.1073/pnas.242603899 . 139241 . 2002PNAS...9916899M . free .
• Guo TB, Boros LG, Chan KC, etal . Spermatogenetic expression of RNA-binding motif protein 7, a protein that interacts with splicing factors. . J. Androl. . 24 . 2 . 204–14 . 2003 . 12634307 . 10.1002/j.1939-4640.2003.tb02664.x.
• Tai HH, Geisterfer M, Bell JC, etal . CHD1 associates with NCoR and histone deacetylase as well as with RNA splicing proteins. . Biochem. Biophys. Res. Commun. . 308 . 1 . 170–6 . 2003 . 12890497 . 10.1016/S0006-291X(03)01354-8 .
• Li J, Hawkins IC, Harvey CD, etal . Regulation of alternative splicing by SRrp86 and its interacting proteins. . Mol. Cell. Biol. . 23 . 21 . 7437–47 . 2003 . 14559993 . 10.1128/MCB.23.21.7437-7447.2003 . 207616 .
• Ota T, Suzuki Y, Nishikawa T, etal . Complete sequencing and characterization of 21,243 full-length human cDNAs. . Nat. Genet. . 36 . 1 . 40–5 . 2004 . 14702039 . 10.1038/ng1285 . free .
• Dettwiler S, Aringhieri C, Cardinale S, etal . Distinct sequence motifs within the 68-kDa subunit of cleavage factor Im mediate RNA binding, protein-protein interactions, and subcellular localization. . J. Biol. Chem. . 279 . 34 . 35788–97 . 2005 . 15169763 . 10.1074/jbc.M403927200 . 39752996 . free .
• Lehner B . Sanderson CM . A protein interaction framework for human mRNA degradation. . Genome Res. . 14 . 7 . 1315–23 . 2004 . 15231747 . 10.1101/gr.2122004 . 442147 .

Notes and References

1. Zahler AM . Lane WS . Stolk JA . Roth MB . SR proteins: a conserved family of pre-mRNA splicing factors . Genes Dev . 6 . 5 . 837–47 . Jun 1992 . 1577277 . 10.1101/gad.6.5.837 . free .
2. Web site: Entrez Gene: SFRS3 splicing factor, arginine/serine-rich 3.
3. Guo . Taylor B . Boros Laszlo G . Chan Kam C . Hikim Amiya P Sinha . Hudson Alan P . Swerdloff Ronald S . Mitchell Aaron P . Salameh Wael A . 2003. Spermatogenetic expression of RNA-binding motif protein 7, a protein that interacts with splicing factors . J. Androl. . 24 . 2 . 204–14 . 0196-3635. 12634307 . 10.1002/j.1939-4640.2003.tb02664.x.