SERINC3 explained

Serine incorporator 3 is a protein that in humans is encoded by the SERINC3 gene.^{[1] [2]} It has been demonstrated that SERINC3 acts as a retrovirus restriction factor. ^{[3] [4] [5]}

Further reading

• Adams MD, Kerlavage AR, Fleischmann RD, Fuldner RA, Bult CJ, Lee NH, Kirkness EF, Weinstock KG, Gocayne JD, White O . Initial assessment of human gene diversity and expression patterns based upon 83 million nucleotides of cDNA sequence . Nature . 377 . 6547 Suppl . 3–174 . September 1995 . 7566098 . .
• Maruyama K, Sugano S . Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides . Gene . 138 . 1–2 . 171–4 . January 1994 . 8125298 . 10.1016/0378-1119(94)90802-8 .
• Bonaldo MF, Lennon G, Soares MB . Normalization and subtraction: two approaches to facilitate gene discovery . Genome Research . 6 . 9 . 791–806 . September 1996 . 8889548 . 10.1101/gr.6.9.791 . free .
• Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, Suyama A, Sugano S . Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library . Gene . 200 . 1–2 . 149–56 . October 1997 . 9373149 . 10.1016/S0378-1119(97)00411-3 .
• Bossolasco M, Veillette F, Bertrand R, Mes-Masson AM . Human TDE1, a TDE1/TMS family member, inhibits apoptosis in vitro and stimulates in vivo tumorigenesis . Oncogene . 25 . 33 . 4549–58 . August 2006 . 16547497 . 10.1038/sj.onc.1209488 . 24696947 .

Notes and References

1. Bossolasco M, Lebel M, Lemieux N, Mes-Masson AM . The human TDE gene homologue: localization to 20q13.1-13.3 and variable expression in human tumor cell lines and tissue . Molecular Carcinogenesis . 26 . 3 . 189–200 . November 1999 . 10559794 . 10.1002/(SICI)1098-2744(199911)26:3<189::AID-MC8>3.0.CO;2-T . 19505445 .
2. Web site: Entrez Gene: SERINC3 serine incorporator 3.
3. Rosa A, Chande A, Ziglio S, De Sanctis V, Bertorelli R, Goh SL, McCauley SM, Nowosielska A, Antonarakis SE, Luban J, Santoni FA, Pizzato M . HIV-1 Nef promotes infection by excluding SERINC5 from virion incorporation . Nature . 526 . 7572 . 212–7 . October 2015 . 26416734 . 10.1038/nature15399 . 4861059 . 2015Natur.526..212R .
4. Chande A, Cuccurullo EC, Rosa A, Ziglio S, Carpenter S, Pizzato M . S2 from equine infectious anemia virus is an infectivity factor which counteracts the retroviral inhibitors SERINC5 and SERINC3 . Proceedings of the National Academy of Sciences of the United States of America . 113 . 46 . 13197–13202 . November 2016 . 27803322 . 10.1073/pnas.1612044113 . 5135340 . free .
5. bioRxiv . 10.1101/2020.02.24.962506 . Coevolution of retroviruses with SERINCs following whole-genome duplication divergence . Ramdas . Pavitra . Bhardwaj . Vipin . Singh . Aman . Vijay . Nagarjun . Chande . Ajit . 2020-02-24 . free .