SEMA6C explained
Semaphorin-6C is a protein that in humans is encoded by the SEMA6C gene.[1] [2]
This gene product is a member of the semaphoring family of proteins. Semaphorins represent important molecular signals controlling multiple aspects of the cellular response that follows CNS injury, and thus may play an important role in neural regeneration.[3]
Further reading
- Pasterkamp RJ, Verhaagen J . Emerging roles for semaphorins in neural regeneration. . Brain Res. Brain Res. Rev. . 35 . 1 . 36–54 . 2001 . 11245885 . 10.1016/S0165-0173(00)00050-3 . 20402160 .
- Gregory SG, Barlow KF, McLay KE, etal . The DNA sequence and biological annotation of human chromosome 1. . Nature . 441 . 7091 . 315–21 . 2006 . 16710414 . 10.1038/nature04727 . 2006Natur.441..315G . free .
- Imabayashi H, Mori T, Gojo S, etal . Redifferentiation of dedifferentiated chondrocytes and chondrogenesis of human bone marrow stromal cells via chondrosphere formation with expression profiling by large-scale cDNA analysis. . Exp. Cell Res. . 288 . 1 . 35–50 . 2003 . 12878157 . 10.1016/S0014-4827(03)00130-7 .
- Strausberg RL, Feingold EA, Grouse LH, etal . Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. . Proc. Natl. Acad. Sci. U.S.A. . 99 . 26 . 16899–903 . 2003 . 12477932 . 10.1073/pnas.242603899 . 139241 . 2002PNAS...9916899M . free .
- Nagase T, Nakayama M, Nakajima D, etal . Prediction of the coding sequences of unidentified human genes. XX. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. . DNA Res. . 8 . 2 . 85–95 . 2001 . 11347906 . 10.1093/dnares/8.2.85 . free .
- Yu W, Andersson B, Worley KC, etal . Large-scale concatenation cDNA sequencing. . Genome Res. . 7 . 4 . 353–8 . 1997 . 9110174 . 10.1101/gr.7.4.353. 139146 .
- Andersson B, Wentland MA, Ricafrente JY, etal . A "double adaptor" method for improved shotgun library construction. . Anal. Biochem. . 236 . 1 . 107–13 . 1996 . 8619474 . 10.1006/abio.1996.0138 .
Notes and References
- Qu X, Wei H, Zhai Y, Que H, Chen Q, Tang F, Wu Y, Xing G, Zhu Y, Liu S, Fan M, He F . Identification, characterization, and functional study of the two novel human members of the semaphorin gene family . J Biol Chem . 277 . 38 . 35574–85 . Sep 2002 . 12110693 . 10.1074/jbc.M206451200 . free .
- Web site: Entrez Gene: SEMA6C sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6C.
- Web site: Entrez Gene: SEMA6C sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6C.
