SEMA3C explained

Semaphorin-3C is a protein that in humans is encoded by the SEMA3C gene.^{[1] [2] [3]}

Further reading

• Robertson NG, Khetarpal U, Gutiérrez-Espeleta GA, Bieber FR, Morton CC . Isolation of novel and known genes from a human fetal cochlear cDNA library using subtractive hybridization and differential screening . Genomics . 23 . 1 . 42–50 . September 1994 . 7829101 . 10.1006/geno.1994.1457 .
• Bonaldo MF, Lennon G, Soares MB . Normalization and subtraction: two approaches to facilitate gene discovery . Genome Research . 6 . 9 . 791–806 . September 1996 . 8889548 . 10.1101/gr.6.9.791 . free .
• Chen H, Chédotal A, He Z, Goodman CS, Tessier-Lavigne M . Neuropilin-2, a novel member of the neuropilin family, is a high affinity receptor for the semaphorins Sema E and Sema IV but not Sema III . Neuron . 19 . 3 . 547–59 . September 1997 . 9331348 . 10.1016/S0896-6273(00)80371-2 . 17985062 . free .
• Yamada T, Endo R, Gotoh M, Hirohashi S . Identification of semaphorin E as a non-MDR drug resistance gene of human cancers . Proceedings of the National Academy of Sciences of the United States of America . 94 . 26 . 14713–8 . December 1997 . 9405678 . 25101 . 10.1073/pnas.94.26.14713 . 1997PNAS...9414713Y . free .
• Galani E, Sgouros J, Petropoulou C, Janinis J, Aravantinos G, Dionysiou-Asteriou D, Skarlos D, Gonos E . Correlation of MDR-1, nm23-H1 and H Sema E gene expression with histopathological findings and clinical outcome in ovarian and breast cancer patients . Anticancer Research . 22 . 4 . 2275–80 . 2002 . 12174914 .
• Rieger J, Wick W, Weller M . Human malignant glioma cells express semaphorins and their receptors, neuropilins and plexins . Glia . 42 . 4 . 379–89 . June 2003 . 12730958 . 10.1002/glia.10210 . 45643250 .
• Miller LE, Weidler C, Falk W, Angele P, Schaumburger J, Schölmerich J, Straub RH . Increased prevalence of semaphorin 3C, a repellent of sympathetic nerve fibers, in the synovial tissue of patients with rheumatoid arthritis . Arthritis and Rheumatism . 50 . 4 . 1156–63 . April 2004 . 15077297 . 10.1002/art.20110 . free .
• Beckers J, Herrmann F, Rieger S, Drobyshev AL, Horsch M, Hrabé de Angelis M, Seliger B . Identification and validation of novel ERBB2 (HER2, NEU) targets including genes involved in angiogenesis . International Journal of Cancer . 114 . 4 . 590–7 . April 2005 . 15609325 . 10.1002/ijc.20798 . 39883399 . free .
• James G. Herman . Herman JG, Meadows GG . Increased class 3 semaphorin expression modulates the invasive and adhesive properties of prostate cancer cells . International Journal of Oncology . 30 . 5 . 1231–8 . May 2007 . 17390026 . 10.3892/ijo.30.5.1231 . free .

Notes and References

1. Püschel AW, Adams RH, Betz H . Murine semaphorin D/collapsin is a member of a diverse gene family and creates domains inhibitory for axonal extension . Neuron . 14 . 5 . 941–8 . May 1995 . 7748561 . 10.1016/0896-6273(95)90332-1 . free .
2. Mangasser-Stephan K, Dooley S, Welter C, Mutschler W, Hanselmann RG . Identification of human semaphorin E gene expression in rheumatoid synovial cells by mRNA differential display . Biochemical and Biophysical Research Communications . 234 . 1 . 153–6 . May 1997 . 9168980 . 10.1006/bbrc.1997.6607 .
3. Web site: Entrez Gene: SEMA3C sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C.