DLGAP3 explained

Disks large-associated protein 3 (DAP-3) also known as SAP90/PSD-95-associated protein 3 (SAPAP-3) is a protein that in humans is encoded by the DLGAP3 gene.

Clinical significance

Mutations in DLGAP3 have been associated with trichotillomania.^[1]

Notes and References

1. Züchner S, Wendland JR, Ashley-Koch AE, Collins AL, Tran-Viet KN, Quinn K, Timpano KC, Cuccaro ML, Pericak-Vance MA, Steffens DC, Krishnan KR, Feng G, Murphy DL . 6 . Multiple rare SAPAP3 missense variants in trichotillomania and OCD . Molecular Psychiatry . 14 . 1 . 6–9 . January 2009 . 19096451 . 2803344 . 10.1038/mp.2008.83 .