S10 ribosomal protein leader explained

Ribosomal S10 leader
Symbol:	S10
Rna Type:	Cis-reg leader
Tax Domain:	Bacteria

S10 ribosomal protein leader is a ribosomal protein leader involved in the ribosome biogenesis. It is used as an autoregulatory mechanism to control the concentration of the ribosomal protein S10. Known Examples were predicted in Clostridia^[1] or other lineages of Bacillota^[2] with bioinformatic approaches. The structure is located in the 5′ untranslated regions of mRNAs encoding ribosomal proteins S10 (rpsJ), L3 (rplc) and L4 (rplD).^[1] There is an uncertainty about the ligand, because of a lack of experimental investigation.

See also

• Ribosomal protein leader

Notes and References

1. Eckert . I . Weinberg . Z . Discovery of 20 novel ribosomal leader candidates in bacteria and archaea . BMC Microbiology . 20 . 130 . 24 May 2020 . 130 . 10.1186/s12866-020-01823-6 . 32448158 . 7247131 . free .
2. Yao . Z . Barrick . J . Weinberg . Z . Neph . S . Breaker . R . Tompa . M . Ruzzo . WL . A computational pipeline for high-throughput discovery of cis-regulatory noncoding RNA in prokaryotes . PLOS Computational Biology . 3 . 7 . 2007 . e126 . 10.1371/journal.pcbi.0030126 . 17616982 . 1913097 . 2007PLSCB...3..126Y . free .