S-Allylcysteine Explained

S-Allylcysteine (SAC) is an organosulfur compound that has the formula . It is the S-allylated derivative of the amino acid cysteine. As such only the L-enantiomer is significant biologically. SAC constituent of aged garlic. A number of related compounds are found in garlic, including the disulfide S-"allylmercaptocysteine" (SAMC,) and γ-glutamyl-S-allylcysteine" (GSAC).[1]

Allylcysteine is of interest for its potential medicinal properties.[2] and as a chemopreventive.[3]

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Notes and References

  1. 10.1021/acs.jafc.8b02541. Changes of S-Allylmercaptocysteine and γ-Glutamyl-S-allylmercaptocysteine Contents and Their Putative Production Mechanisms in Garlic Extract during the Aging Process. 2018. Fujii. Takuto. Matsutomo. Toshiaki. Kodera. Yukihiro. Journal of Agricultural and Food Chemistry. 66. 40. 10506–10512. 30226990. 52297055 .
  2. Yeh YY, Liu L . Cholesterol-lowering effect of garlic extracts and organosulfur compounds: human and animal studies . Journal of Nutrition . 2001 . 131 . 3s . 989S–93S . 10.1093/jn/131.3.989S . 11238803. free .
  3. 10.2174/1573394054021772 . Arora, Annu . Tripathi, Chitra . Shukla, Yogeshwer . Garlic and its organosulfides as potential chemopreventive agents: a review . Current Cancer Therapy Reviews . 2005 . 1 . 2 . 199–205.

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