S-14,506 Explained

S-14,506 is a naphthylpiperazine, a 5-HT1A receptor agonist,[1] and a dopamine receptor antagonist.[2]

Notes and References

  1. 11166326 . 2001 . Milligan . G. . Kellett . E. . Dacquet . C. . Dubreuil . V. . Jacoby . E. . Millan . M. J. . Lavielle . G. . Spedding . M. . S 14506: Novel receptor coupling at 5-HT(1A) receptors . Neuropharmacology . 40 . 3 . 334–344 . 10.1016/s0028-3908(00)00162-3 . 36060096 .
  2. 7698199 . 1994 . Protais . P. . Chagraoui . A. . Arbaoui . J. . Mocaër . E. . Dopamine receptor antagonist properties of S 14506, 8-OH-DPAT, raclopride and clozapine in rodents . European Journal of Pharmacology . 271 . 1 . 167–177 . 10.1016/0014-2999(94)90277-1 .

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