| Sérignac | |
| Commune Status: | Commune |
| Arrondissement: | Castelsarrasin |
| Canton: | Beaumont-de-Lomagne |
| Insee: | 82180 |
| Postal Code: | 82500 |
| Mayor: | Christian Lagarde[1] |
| Term: | 2020 - 2026 |
| Intercommunality: | Lomagne Tarn-et-Garonnaise |
| Coordinates: | 43.9219°N 1.0228°W |
| Elevation M: | 220 |
| Elevation Min M: | 89 |
| Elevation Max M: | 230 |
| Area Km2: | 32.43 |
Sérignac (in French pronounced as /seʁiɲak/; Occitan (post 1500);: Serinhac) is a commune in the Tarn-et-Garonne department in the Occitanie region in southern France.