| São Sebastião do Uatumã | |
| Settlement Type: | Municipality |
| Pushpin Map Caption: | Location in Brazil |
| Subdivision Type: | Country |
| Subdivision Name: |  Brazil |
| Subdivision Name1: | North |
| Subdivision Name2: | Amazonas |
| Population As Of: | 2020[1] |
| Population Total: | 14,352 |
| Timezone: | AMT |
| Utc Offset: | -4 |
| Coordinates: | -2.5719°N -57.8708°W |
São Sebastião do Uatumã is a municipality located in the Brazilian state of Amazonas. Its population was 14,352 (2020) and its area is 10,741 km2.[2]
The municipality contains part of the Uatumã Biological Reserve, a strictly protected conservation unit created in 2002.It contains about 60% of the Uatumã Sustainable Development Reserve, which protects the lower part of the Uatumã River basin.