| São Sebastião | |
| Settlement Type: | Administrative region |
| Official Name: | Região Administrativa de São Sebastião Administrative Region of São Sebastião |
| Mapsize: | 250px |
| Subdivision Type: | Country |
| Subdivision Type1: | Region |
| Subdivision Type2: | State |
| Subdivision Name: |  Brazil |
| Subdivision Name1: | Central-West |
| Subdivision Name2: | Federal District |
| Leader Title: | Regional administrator |
| Leader Name: | Alan José Valim Maia |
| Established Title: | Established |
| Established Date: | 25 June 1993 |
| Area Total Km2: | 262.7 |
| Population Total: | 119293 |
| Population Density Km2: | auto |
| Timezone: | UTC-3 |
| Utc Offset: | -3 |
| Timezone Dst: | UTC-2 |
| Utc Offset Dst: | -2 |
| Coordinates: | -15.9006°N -47.7794°W |
| Area Code: | +55 61 |
| Postal Code Type: | Postal Code (CEP) |
São Sebastião is an administrative region in the Federal District in Brazil. São Sebastião was founded on June 25, 1993, receiving the status of administrative region, according to Law 467, of June 25, 1993.