| Type: | parish |
| Official Name: | São Mamede de Infesta |
| Image Location: | LocalFregMatosinhos-SãoMamedeDeInfesta.svg |
| Region: | Norte |
| Metro: | Porto |
| District: | Porto |
| Municipality: | Matosinhos |
| Coordinates: | 41.2°N -44°W |
| Area Total: | 5.21 |
| Population Total: | 23122 |
| Dissolved: | 2013 |
| Postal Code: | 4465-268 |
São Mamede de Infesta, or simply São Mamede, is a former civil parish in the municipality of Matosinhos in the Greater Porto area, Portugal. In 2013, the parish merged into the new parish São Mamede de Infesta e Senhora da Hora.[1] It has a population of approximately 28,000 inhabitants and is located just north of the city of Porto.