| Ryan McDonald | |
| Number: | 50 |
| Position: | Center |
| Birth Date: | 21 September 1985 |
| Birth Place: | Holland, Michigan, U.S. |
| Height Ft: | 6 |
| Height In: | 5 |
| Weight Lbs: | 295 |
| College: | Illinois |
| Undraftedyear: | 2009 |
| Pastteams: | |
| Highlights: |
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| Aflstatlabel1: | Tackles |
| Aflstatvalue1: | 4 |
| Afl: | 11784 |
Ryan McDonald (born September 21, 1985) is a former American football center. He has also played for the San Diego Chargers of the National Football League (NFL). He was signed by the Chargers as an undrafted free agent in 2009.