| Rusty Pence | |
| Position: | Pitcher |
| Bats: | Right |
| Throws: | Right |
| Birth Date: | 11 March 1900 |
| Birth Place: | Marine, Illinois |
| Death Place: | Hot Springs, Arkansas |
| Debutleague: | MLB |
| Debutdate: | May 13 |
| Debutyear: | 1921 |
| Debutteam: | Chicago White Sox |
| Finalleague: | MLB |
| Finaldate: | May 30 |
| Finalyear: | 1921 |
| Finalteam: | Chicago White Sox |
| Statleague: | MLB |
| Stat1label: | Win–loss record |
| Stat1value: | 0–0 |
| Stat2label: | Strikeouts |
| Stat2value: | 2 |
| Stat3label: | Earned run average |
| Stat3value: | 8.44 |
| Teams: | Chicago White Sox (1921) |
Russell William Pence (March 11, 1900 – August 11, 1971) was a Major League Baseball pitcher. He pitched for the Chicago White Sox in 1921.