| Rui Lopes | |
| Fullname: | Rui José Lopes |
| Birth Date: | 1960 3, df=yes |
| Birth Place: | Guinea-Bissau |
| Position: | Forward[1] |
| Years1: | 1982–1984 |
| Clubs1: | Amarante FC |
| Years2: | 1983–1984 |
| Clubs2: | → Leixões (loan) |
| Caps2: | 29 |
| Goals2: | 12 |
| Years3: | 1984–1986 |
| Clubs3: | Rio Ave |
| Caps3: | 43 |
| Goals3: | 14 |
| Years4: | 1986–1987 |
| Clubs4: | FC Famalicão |
| Caps4: | 13 |
| Goals4: | 1 |
| Years5: | 1987–1989 |
| Clubs5: | Fafe |
| Caps5: | 8 |
| Goals5: | 1 |
| Years6: | 1989–1990 |
| Clubs6: | Águeda |
| Caps6: | 25 |
| Goals6: | 4 |
| Years7: | 1990–1991 |
| Clubs7: | Leça |
| Caps7: | 20 |
| Goals7: | 4 |
| Years8: | 1991–1992 |
| Clubs8: | FC Felgueiras |
| Caps8: | 14 |
| Goals8: | 1 |
| Years9: | 1992–1993 |
| Clubs9: | SC Lamego |
| Years10: | 1993–1994 |
| Clubs10: | Trofense |
Rui José Lopes (born 6 March 1960) is a retired Bissau-Guinean footballer who played as a forward.