Ruberlysin Explained

Ruberlysin
Ec Number:3.4.24.48
Cas Number:846020-01-7

Ruberlysin (Crotalus ruber metalloendopeptidase II, hemorrhagic toxin II) is an enzyme.[1] [2] This enzyme catalyses the following chemical reaction

Cleavage of His10-Leu, Ala14-Leu, Tyr16-Leu and Gly23-Phe bonds in the B chain of insulin; His-Pro, Pro-Phe, and Trp-Ser of angiotensin I; and Gly-Phe of Met enkephalin

This endopeptidase is present in the venom of the red rattlesnake (Crotalus ruber ruber).

Notes and References

  1. Mori N, Nikai T, Sugihara H, Tu AT . Biochemical characterization of hemorrhagic toxins with fibrinogenase activity isolated from Crotalus ruber ruber venom . Archives of Biochemistry and Biophysics . 253 . 1 . 108–21 . February 1987 . 2949699 . 10.1016/0003-9861(87)90643-6 .
  2. Takeya H, Onikura A, Nikai T, Sugihara H, Iwanaga S . Primary structure of a hemorrhagic metalloproteinase, HT-2, isolated from the venom of Crotalus ruber ruber . Journal of Biochemistry . 108 . 5 . 711–9 . November 1990 . 2081731 .

This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Ruberlysin".

Except where otherwise indicated, Everything.Explained.Today is © Copyright 2009-2024, A B Cryer, All Rights Reserved. Cookie policy.