| Roupen II Ռուբեն Բ | |
| Lord of Cilicia | |
| Succession: | Lord of Armenian Cilicia |
| Reign: | 1169–1170 |
| Predecessor: | Thoros II |
| Successor: | Mleh I |
| House: | Roupenians |
| Father: | Thoros II |
| Mother: | An unnamed daughter of Regent Thomas |
| Birth Date: | c. 1165 |
| Death Date: | 1170 |
| Death Place: | Hromgla |
Ruben II (Armenian: Ռուբեն Բ), also Roupen II[1] [2] or Rupen II, (c.1165 - 1170) was the seventh lord of Armenian Cilicia[1] (1169–1170).
Roupen was the son of Thoros II, lord of Armenian Cilicia, by his second wife (and great niece) whose name is unknown. Thoros II abdicated in favour of his young son Roupen in 1169, and placed Roupen under the guardianship of the Regent Thomas[1] (Thomas was the child’s maternal grandfather). However, Thoros II’s brother, Mleh disputed the succession; Mleh had fled to Nur ad-Din (the emir of Aleppo) and become a Muslim after quarreling with Thoros II and attempting to assassinate him.[2]
Mleh refused an amicable settlement with Regent Thomas regarding the succession to the leadership of Armenian Cilicia and invaded the country with a force provided by Nur ad-Din.[1] Fearing for Roupen’s life, Thomas entrusted the young child into the care of the patriarch Nerses IV Shnorhali in Hromkla (today Rumkale in Turkey) and fled to Antioch.[1] This measure of caution, however, did not save the life of the young Roupen, who was followed by his uncle’s men and murdered at Hromgla.[1]