| Rube Dessau | |
| Position: | Pitcher |
| Bats: | Switch |
| Throws: | Right |
| Birth Date: | March 29, 1883 |
| Birth Place: | New Galilee, Pennsylvania |
| Death Place: | York, Pennsylvania |
| Debutleague: | MLB |
| Debutdate: | September 22 |
| Debutyear: | 1907 |
| Debutteam: | Boston Doves |
| Finalleague: | MLB |
| Finaldate: | October 12 |
| Finalyear: | 1910 |
| Finalteam: | Brooklyn Superbas |
| Statleague: | MLB |
| Stat1label: | Win–loss record |
| Stat1value: | 2–4 |
| Stat2label: | Earned run average |
| Stat2value: | 6.53 |
| Stat3label: | Strikeouts |
| Stat3value: | 25 |
| Teams: |
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Frank Rolland Dessau (March 29, 1883 – May 6, 1952) was a pitcher in Major League Baseball. He pitched in two games for the 1907 Boston Doves and in nineteen games for the 1910 Brooklyn Superbas. He was also a manager in minor league baseball for the York White Roses, Decatur Commodores, and Springfield Senators over 11 seasons.