RsmW sRNA explained

RsmW sRNA
Rfam:	RF02809
Tax Domain:	Bacteria

RsmW is a part of the Rsm/Csr family of non-coding RNAs (ncRNAs) discovered in Pseudomonas aeruginosa. It specifically binds to RsmA protein in vitro, restores biofilm production (possibly due to the interaction with RsmA) and partially complements the loss of RsmY and RsmZ in rsmY/rsmZ double mutant in regards to their contribution to swarming. Compared to RsmY and RsmZ its production is induced in high temperatures and rsmW is not transcriptionally activated by GacA.^{[1] [2]}

See also

• CsrB/RsmB RNA family
• CsrC RNA family
• PrrB/RsmZ RNA family
• RsmY RNA family
• RsmX
• CsrA protein

Notes and References

1. Miller CL, Romero M, Karna SL, Chen T, Heeb S, Leung KP . RsmW, Pseudomonas aeruginosa small non-coding RsmA-binding RNA upregulated in biofilm versus planktonic growth conditions . BMC Microbiology . 16 . 1 . 155 . July 2016 . 27430253 . 4950607 . 10.1186/s12866-016-0771-y . free .
2. Wurtzel O, Yoder-Himes DR, Han K, Dandekar AA, Edelheit S, Greenberg EP, Sorek R, Lory S . The single-nucleotide resolution transcriptome of Pseudomonas aeruginosa grown in body temperature . PLOS Pathogens . 8 . 9 . e1002945 . September 2012 . 23028334 . 3460626 . 10.1371/journal.ppat.1002945 . free .