| State: | WV |
| Type: | WV |
| Route: | 161 |
| Length Mi: | 20.6 |
| Length Round: | 1 |
| Length Ref: | [1] |
| Direction A: | South |
| Terminus A: | in Bishop |
| Junction: | near Black Wolf |
| Direction B: | North |
| Terminus B: | in Elkhorn |
| Counties: | McDowell |
| Previous Type: | WV |
| Previous Route: | 152 |
| Next Type: | WV |
| Next Route: | 180 |
West Virginia Route 161 is a north - south state highway located entirely within McDowell County, West Virginia. The southern terminus of the route is at West Virginia Route 16 in Bishop less than 900feet from the Virginia state line. The northern terminus is at U.S. Route 52 in Elkhorn.
At Bishop, WV 161 enters Virginia for approximately 500feet. The state line follows Jacobs Fork and Horsepen Creek, which form a tight bend. There are no signs or visual indications of the state line. West Virginia maintains the road in Virginia.