| State: | MO |
| Type: | Route |
| Route: | 156 |
| Map Custom: | yes |
| Map Notes: | MO 156 highlighted in red |
| Length Mi: | 58.715 |
| Established: | 1951[1] |
| Direction B: | East |
| Direction A: | West |
| Terminus B: | in Ewing |
| Junction: | in La Plata |
| Terminus A: | southwest of Kirksville |
| Previous Type: | I |
| Previous Route: | 155 |
| Next Type: | MO |
| Next Route: | 157 |
Route 156 is a highway in northern Missouri. Its eastern terminus is at Route 6 in Ewing; its western terminus is at Route 149 in northwestern Macon County.