Rotavirus cis-acting replication element explained

Rotavirus cis-acting replication element (CRE)
Symbol:Rota_CRE
Rfam:RF00501
Rna Type:Cis-reg
Tax Domain:Viruses

This family represents a rotavirus cis-acting replication element (CRE) found at the 3'-end of rotavirus mRNAs. The family is thought to promote the synthesis of minus strand RNA to form viral dsRNA.[1]

Notes and References

  1. Chen D, Barros M, Spencer E, Patton JT . Features of the 3'-consensus sequence of rotavirus mRNAs critical to minus strand synthesis . Virology . 282 . 2 . 221–229 . April 2001 . 11289804 . 10.1006/viro.2001.0825 . free .