| Rosario River | |
| Source1 Location: | Cuchilla Grande Inferior |
| Mouth: | Rio de la Plata |
| Mouth Coordinates: | -34.4334°N -57.3505°W |
| Subdivision Type1: | Country |
| Subdivision Name1: | Uruguay |
| Length: | 80km (50miles)[1] |
| Basin Size: | 1745km2[2] |
The Rosario River (es|Río Rosario) is a river located in the Colonia Department of Uruguay. Its originates in Cuchilla Grande Inferior, near the limit with the departments of San José, Flores, and Soriano, and flows into the Río de la Plata.