| Jurisdiction: | Diocese |
| Uruaçu | |
| Latin: | Dioecesis Uruassuensis |
| Local: | Diocese de Uruaçu |
| Country: | Brazil |
| Rite: | Latin Rite |
| Established: | 26 March 1956 (years ago) |
| Cathedral: | Cathedral of St Anne in Uruaçu |
| Area Km2: | 43,000 |
| Population: | 376,000 |
| Population As Of: | 2010 |
| Catholics: | 319,000 |
| Catholics Percent: | 84.8 |
| Bishop: | Giovanni Carlos Caldas Barroca |
| Emeritus Bishops: | José da Silva Chaves |
| Map: | DiocesisGoiasDistritoFederal.jpg |
The Roman Catholic Diocese of Uruaçu (Latin: Dioecesis Uruassuensis) is a diocese located in the city of Uruaçu in the ecclesiastical province of Brasília in Brazil.
On June 17, 2020, Giovanni Carlos Caldas Barroca, a priest of the Brasilia archdiocese, was appointed the new Bishop here.