| Jurisdiction: | Diocese |
| Trujillo | |
| Latin: | Dioecesis Truxillensis in Venetiola |
| Country: | Venezuela |
| Rite: | Latin Rite |
| Established: | 4 June 1957 (years ago) |
| Cathedral: | Catedral Nuestra Señora de la Paz |
| Area Km2: | 7,400 |
| Population: | 712,697 |
| Population As Of: | 2004 |
| Catholics: | 677,062 |
| Catholics Percent: | 95.0 |
| Bishop: | José Trinidad Fernández Angulo |
| Map: | Diócesis de Trujillo.svg |
The Roman Catholic Diocese of Trujillo (Latin: Dioecesis Truxillensis in Venetiola) is a diocese located in the city of Trujillo in the ecclesiastical province of Mérida in Venezuela.
On 4 June 1957 Pope Pius XII established the Diocese of Trujillo from the Metropolitan Archdiocese of Mérida.
The episcopal headquarters is in the city of Trujillo, where the Cathedral of Our Lady of Peace is located.
Its territory is divided into 79 parishes, a Rectory and a Vicariate.